Results 21 to 30 of about 39,409 (160)

Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication [PDF]

, 2021
International audienceAs coronaviruses (CoVs) replicate in the host cell cytoplasm, they rely on their own capping machinery to ensure the efficient translation of their mRNAs, protect them from degradation by cellular 5- exoribonucleases, and escape ...
Canard, B., Snijder, E.J., Ogando, Natacha, S, El Kazzi, Priscila, Ferron, Francois, Snijder, Eric J, Ogando, Natacha S, Posthuma, Clara C, Snijder, Eric, J, Posthuma, C.C., Zevenhoven-Dobbe, Jessika C, Zevenhoven-Dobbe, J.C., Zevenhoven-Dobbe, Jessika, C, Bontes, Brenda, W, Ogando, N.S., Canard, Bruno, Thiel, Volker, Decombe, Alice, Posthuma, Clara, C S, Thiel, V., Bontes, Brenda W, Kazzi, P. el, Ferron, F., Bontes, B.W., Decroly, E., Decroly, Etienne, Decombe, A.   +26 more
core   +2 more sources

The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner

Viruses, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible RNA virus that is the causative agent of the Coronavirus disease 2019 (COVID-19) pandemic.
Victoria Callahan, Seth Hawks, Matthew A. Crawford, Caitlin W. Lehman, Holly A. Morrison, Hannah M. Ivester, Ivan Akhrymuk, Niloufar Boghdeh, Rafaela Flor, Carla V. Finkielstein, Irving Coy Allen, James Weger-Lucarelli, Nisha Duggal, Molly A. Hughes, Kylene Kehn-Hall   +14 more
doaj   +1 more source

Highly conserved Betacoronavirus sequences are broadly recognized by human T cells [PDF]

Cell
Alba Grifoni
exaly   +2 more sources

CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology

Vaccines, 2021
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain.
Jennifer K. DeMarco, Joshua M. Royal, William E. Severson, Jon D. Gabbard, Steve Hume, Josh Morton, Kelsi Swope, Carrie A. Simpson, John W. Shepherd, Barry Bratcher, Kenneth E. Palmer, Gregory P. Pogue   +11 more
doaj   +1 more source

Comparative Study of Blue Light with Ultraviolet (UVC) Radiation on Betacoronavirus 1

Applied Sciences, 2023
The ongoing coronavirus pandemic requires more effective disinfection methods. Disinfection using ultraviolet light (UV), especially longer UVC wavelengths, such as 254 and 270/280 nm, has been proven to have virucidal properties, but its adverse effects
Kritika Vashishtha, Fengfeng Xi, Priya Dharmalingam, Alexandre Douplik   +3 more
doaj   +1 more source

Etiology of epidemic outbreaks COVID-19 in Wuhan, Hubei province, Chinese People Republic associated with 2019-nCoV (Nidovirales, Coronaviridae, Coronavirinae, Betacoronavirus, Subgenus Sarbecovirus): lessons of SARS-CoV outbreak

Вопросы вирусологии, 2020
Results of analysis of phylogenetic, virological, epidemiological, ecological, clinical data of COVID-19 outbreaks in Wuhan, China (PRC) in comparison with SARS-2002 and MERS-2012 outbreaks allow to conclude: – the etiological agent of COVID-19 is ...
D. K. Lvov, S. V. Alkhovsky, L. V. Kolobukhina, E. I. Burtseva   +3 more
doaj   +1 more source

Seroprevalence and Risk Factors for Bovine Coronavirus Infection among Dairy Cattle and Water Buffalo in Campania Region, Southern Italy

Animals, 2023
Cattle and water buffalo are the main livestock species that are raised in the Campania region, southern Italy, and they contribute significantly to the regional rural economy.
Gianmarco Ferrara, Valentina Iovane, Elvira Improda, Giuseppe Iovane, Ugo Pagnini, Serena Montagnaro   +5 more
doaj   +1 more source

Study of the Antiviral Activity of Adamantane-Containing Chemical Compounds

Антибиотики и Химиотерапия, 2022
Influenza and coronavirus infections are especially dangerous due to being capable of causing pandemics and clinical complications in the nervous and cardiovascular systems, as well as exacerbation of chronic diseases (diabetes mellitus, heart failure ...
I. I. LYUBIMOV, E. I. ISAEVA, E. N. VETROVA, A. V. LAVROVA, N. M. GRETSKAYA, I. V. SERKOV, V. V. BEZUGLOV, G. A. GALEGOV   +7 more
doaj   +1 more source

Diplejía facial aislada como variante atípica del síndrome de Guillain-Barré tras sospecha de infección por SARS-CoV-2

Revista de la Facultad de Ciencias Médicas de Córdoba, 2021
Introducción: Desde que se inició la pandemia por el SARS-CoV-2, se han descrito numerosos casos de síndrome de Guillain-Barré secundario a la COVID-19.
Cristina Lavilla Olleros, Marina López-Rubio, Chiara Fanciulli, Adriana González-Munera, Jesús Millán Núñez-Cortés   +4 more
doaj   +1 more source

Betacoronavirus-specific alternate splicing.

, 2022
Viruses can subvert a number of cellular processes including splicing in order to block innate antiviral responses, and many viruses interact with cellular splicing machinery.
Beheshti, Afshin, Baylin, Stephen B, Butler, Daniel, Mozsary, Christopher, Robinson, Peter N, Wurtele, Eve, Saravia-Butler, Amanda M, Aronow, Bruce, Karlebach, Guy, Levy, Shawn, Foox, Jonathan, Meydan, Cem, Taylor, Deanne M, Mason, Christopher E   +13 more
core   +1 more source