Results 91 to 100 of about 43,853 (237)

Heterogeneous Evolution Among SARS‐CoV‐2 Genes and Variants of Concern

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT Challenges persist regarding the influence of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) on public health, with growing interest in future viral molecular variants. In this context, accurate predictions demand a thorough understanding of the virus's molecular evolution, especially proteins targeted by therapies, where ...
Luis Daniel González‐Vázquez, Paula Iglesias‐Rivas, David Ferreiro, Miguel Arenas   +3 more
wiley   +1 more source

SARS-CoV-2: estructura, replicación y mecanismos fisiopatológicos relacionados con COVID-19

Gaceta Médica Boliviana, 2020
SARS-CoV2 es causante del síndrome respiratorio agudo severo, enfermedad que ha sido también nombrada COVID-19, fue notificado a fines del año 2019 como un nuevo betacoronavirus en personas expuestas en un mercado de mariscos en Wuhan, China.
Gabriela Antezana Llaveta, Jaime Arandia-Guzmán   +1 more
doaj   +1 more source

Pitfalls and perils of survival analysis under incorrect assumptions: the case of COVID-19 data

Biomédica: revista del Instituto Nacional de Salud, 2021
Non-parametric survival analysis has become a very popular statistical method in current medical research. However, resorting to survival analysis when its fundamental assumptions are not fulfilled can severely bias the results.
Daniele Piovani, Georgios K. Nikolopoulos, Stefanos Bonovas   +2 more
doaj   +1 more source

The Small Cysteine‐Rich Protein of Potato Mop‐Top Virus Exhibits Viroporin Activity

Molecular Plant Pathology, Volume 26, Issue 9, September 2025.
The cysteine‐rich 8K protein of PMTV exhibits a viroporin activity that forms multimers on endomembrane, alters membrane permeability, and conducts potassium and protons. ABSTRACT Potato mop‐top virus (PMTV) is the causal agent of potato tuber spraing disease, which causes significant economic losses to potato production worldwide.
Ye Liu, Xinyue Fan, Yameng Luan, Yong Li, Yu Zhao, Weiqin Ji, Naihui Li, Xiaoyun Wu, Xiaofei Cheng, Yanju Bai   +9 more
wiley   +1 more source

Detecting and Monitoring Porcine Hemagglutinating Encephalomyelitis Virus, an Underresearched Betacoronavirus

mSphere, 2020
There is a paucity of information concerning the ecology of porcine hemagglutinating encephalomyelitis virus (PHEV) in commercial swine herds. This study provided evidence that PHEV infection is endemic and highly prevalent in U.S. swine herds. These results raised questions for future studies regarding the impact of endemic PHEV on swine health and ...
Mora-Díaz, Juan Carlos, Magtoto, Ronaldo, Houston, Elizabeth, Baum, David, Carrillo-Ávila, José Antonio, Temeeyasen, Gun, Zimmerman, Jeff, Piñeyro, Pablo, Giménez-Lirola, Luis   +8 more
openaire   +6 more sources

Extension of the known distribution of a novel clade C betacoronavirus in a wildlife host [PDF]

Epidemiology and Infection, 2019
AbstractDisease surveillance in wildlife populations presents a logistical challenge, yet is critical in gaining a deeper understanding of the presence and impact of wildlife pathogens. Erinaceus coronavirus (EriCoV), a clade C Betacoronavirus, was first described in Western European hedgehogs (Erinaceus europaeus) in Germany.
I. F. Saldanha, B. Lawson, H. Goharriz, J. Rodriguez-Ramos Fernandez, S. K. John, A. R. Fooks, A. A. Cunningham, N. Johnson, D. L. Horton   +8 more
openaire   +6 more sources

Multimorbidity patterns among COVID-19 deaths: proposal for the construction of etiological models

Revista Panamericana de Salud Pública, 2020
Objectives. To describe patterns of multimorbidity among fatal cases of COVID-19, and to propose a classification of patients based on age and multimorbidity patterns to begin the construction of etiological models. Methods.
Julián A. Fernández-Niño, John A. Guerra-Gómez, Alvaro J. Idrovo   +2 more
doaj   +1 more source

Prevalence and factors associated with the intention to vaccinate against COVID-19 in Peru

Revista Peruana de Medicina Experimental y Salud Pública, 2021
Objectives: To estimate the prevalence and factors associated with COVID-19 vaccination intention (VI) in Peru. Materials and methods: Analytical cross-sectional study using the survey conducted by the University of Maryland, USA, on Facebook.
Percy Herrera-Añazco, Ángela Uyen-Cateriano, Diego Urrunaga-Pastor, Guido Bendezu-Quispe, Carlos J. Toro-Huamanchumo, Alfonso J. RodrÍguez-Morales, Adrian V. Hernández, Vicente A. Benites-Zapata   +7 more
doaj   +1 more source

Aging Compromises Terminal Differentiation Program of Cytotoxic Effector Lineage and Promotes Exhaustion in CD8+ T Cells Responding to Coronavirus Infection

Aging Cell, Volume 24, Issue 8, August 2025.
In a MHV infection model with age‐associated increased mortality, we demonstrate that aging impairs, instead of promoting, the terminal differentiation program of virus‐specific CD8+ T cells through downregulating key transcriptional regulators of terminal differentiation.
Ziang Zhu, Guohua Lou, Ying Luo, Kiddist Yihunie, Jonathan Hoar, Juan A. Daniel, Bret M. Evers, Chen Yao, Tuoqi Wu   +8 more
wiley   +1 more source

Transiciones entre los estados de diagnóstico de personas con la COVID-19 en Colombia

Revista Panamericana de Salud Pública, 2020
Objetivo. Determinar las probabilidades de transición entre distintos tipos de atención y estados para la población infectada con la COVID-19 en Colombia, por grupos de edad. Métodos.
Luis Carlos Manrique Ruiz, Guberney Muñetón Santa, Osmar Leandro Loaiza Quintero   +2 more
doaj   +1 more source