Results 11 to 20 of about 43,853 (237)
Betacoronavirus internal protein: role in immune evasion and viral pathogenesis. [PDF]
J VirolABSTRACT Betacoronaviruses express a small internal (I) protein that is encoded by the same subgenomic RNA (sgRNA) as the nucleocapsid (N) protein. Translation of the +1 reading frame of the N sgRNA through leaky ribosomal scanning leads to expression of the I protein.
Gunawardene CD, Wong L-YR.
europepmc +4 more sources
Identification, Isolation, and Molecular Characterization of Betacoronavirus in Oryx leucoryx
Microbiology Spectrum, 2023 Coronaviruses (CoVs) are enveloped viruses with a large RNA genome (26 to 32 kb) and are classified into four genera: Alphacoronavirus, Betacoronavirus, Gammacoronavirus, and Deltacoronavirus.
Dan David +8 more
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Betacoronavirus-specific alternate splicing [PDF]
Genomics, 2021 AbstractViruses can subvert a number of cellular processes in order to block innate antiviral responses, and many viruses interact with cellular splicing machinery. SARS-CoV-2 infection was shown to suppress global mRNA splicing, and at least 10 SARS-CoV-2 proteins bind specifically to one or more human RNAs.
Guy Karlebach +13 more
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Group C Betacoronavirus in Bat Guano Fertilizer, Thailand [PDF]
Emerging Infectious Diseases, 2013 To the Editor: Bats play a critical role in the transmission and origin of zoonotic diseases, primarily viral zoonoses associated with high case-fatality rates, including those caused by Nipah virus (NiV) and severe acute respiratory syndrome (SARS)–like coronavirus (CoV) infections (1).
Supaporn Wacharapluesadee +11 more
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A potential broad‐spectrum neutralizing antibody against Betacoronavirus [PDF]
Journal of Medical Virology, 2023 AbstractThree pandemics caused by human Betacoronavirus had broken out in the past two decades. Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) was one of the novel epidemic strains which caused the third pandemic, coronavirus disease 2019 (COVID‐19), a global public health crisis.
Rong Wang +11 more
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Betacoronavirus Infection Outbreak, São Paulo, Brazil, Fall 2023
Emerging Infectious DiseasesWe report a human coronavirus OC43 infection outbreak in hospitalized patients and healthcare workers in São Paulo, Brazil, occurring after SARS-CoV-2 cases disappeared. Infection was associated with healthcare workers in 5 (29.4%) patients.
Tânia do Socorro Souza Chaves +4 more
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Structural proteins in the mechanisms of betacoronavirus virion assembly [PDF]
The Ukrainian Biochemical Journal, 2022 The emergence of SARS-CoV-2 caused an urgent need to investigate the molecular mechanisms of its reproduction. However, the detailed step-by-step mechanism of SARS-CoV-2 virion assembly has not been described yet. In the presented review the data on the role of structural proteins in the efficient assembly of betacoronavirus particles are analyzed.
I. Zaloilo +3 more
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Conserved host-pathogen interactions identify novel treatment options in betacoronavirus infections [PDF]
Signal Transduction and Targeted Therapy, 2021 Hypoxia is an underlying pathophysiological condition of a variety of devastating diseases, including acute ischemic stroke (AIS). We are faced with limited therapeutic options for AIS patients, and even after successful restoration of cerebral blood flow, the poststroke mortality is still high.
Soeren Lukassen, Roland Eils
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Sars-Cov-2 And Betacoronavirus: What Have We Learned In 8 Months? [PDF]
Postępy Mikrobiologii - Advancements of Microbiology, 2020 Abstract In 2019, a new human pandemic coronavirus (SARS-CoV-2) emerged in Wuhan, China. We present the knowledge about SARS-CoV-2 compared to SARS-CoV and MERS-CoV. The SARS-CoV-2 is similar to other coronaviruses, nevertheless, differences were observed. Cell entry of SARS-CoV-2 is facilitated by cleavage of spike protein by furin. The
Agnieszka Kwiatek +1 more
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Identification of the Receptor-Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 [PDF]
Journal of Virology, 2015 ABSTRACT Coronavirus spike (S) glycoproteins mediate receptor binding, membrane fusion, and virus entry and determine host range. Murine betacoronavirus (β-CoV) in group A uses the N-terminal domain (NTD) of S protein to bind to its receptor, whereas the β-CoVs severe acute respiratory syndrome CoV in group B and Middle East respiratory ...
Zhaohui Qian +6 more
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