Results 201 to 210 of about 41,690 (230)

The host protease KLK5 primes and activates spike proteins to promote human betacoronavirus replication and lung inflammation

Science Signaling
Coronaviruses rely on host proteases to activate the viral spike protein, which facilitates fusion with the host cell membrane and the release of viral genomic RNAs into the host cell cytoplasm.
Hyunjoon Kim, Yeonglim Kang, Semi Kim, Dongbin Park, Seo-Young Heo, Ji-Seung Yoo, Isaac Choi, Monford Paul Abishek N, Jae-Woo Ahn, Jeong-Sun Yang, Nayeon Bak, K. Kim, Joo-Yeon Lee, Young-Ki Choi   +13 more
semanticscholar   +1 more source

Middle east respiratory syndrome coronavirus (MERS-CoV): An underestimated betacoronavirus with pandemic potential.

Diagnostic microbiology and infectious disease
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic beta coronavirus identified in 2012 that circulates in dromedary camels and occasionally infects humans.
Sijo Asokan, I. Isiaka, Teena Jacob, Smitha Vijayan, Divya Rajeswary   +4 more
semanticscholar   +1 more source

A Biosafety Level 2 Mouse Model for Studying Betacoronavirus-Induced Acute Lung Damage and Systemic Manifestations.

Journal of Virology, 2021
Cristina Guatimosim, Ricardo Durães-Carvalho, Vivian V Costa   +2 more
exaly  

Dasatinib inhibits betacoronavirus replication in macrophages and attenuates pro-inflammatory mediators via SRC-MAPK pathway modulation

Medical Microbiology and Immmunology
Ana Carolina Santos Ricoy, M. P. Braga, T. Lacerda, Flávia Rayssa Braga Martins, A. C. Mendes, M. Teixeira, V. Costa, Diana Bahia, F. Soriani   +8 more
semanticscholar   +1 more source

Recombination and Positive Selection Differentially Shaped the Diversity of Betacoronavirus Subgenera

Viruses, 2020
Diego Forni, Manuela Sironi, Rachele Cagliani   +2 more
exaly  

The Betacoronavirus PHEV Replicates and Disrupts the Respiratory Epithelia and Upregulates Key Pattern Recognition Receptor Genes and Downstream Mediators, Including IL-8 and IFN-λ.

MSphere, 2021
Rahul K Nelli, Juan Mora-Díaz, Luis Giménez-Lirola   +2 more
exaly  

BETACORONAVIRUS ATTENUATED STRAIN

2023
TAKEKAWA SHIRO, EBINA HIROTAKA, OKAMURA SHINYA, KASHIWABARA AKIHO   +3 more
openaire   +1 more source

BETACORONAVIRUS PROPHYLAXIS AND THERAPY

2021
FREDRIKSEN AGNETE, SEKELJA MONIKA, SCHJETNE KAROLINE, NORHEIM GUNNSTEIN, STUBSRUD ELISABETH   +4 more
openaire   +3 more sources

Conserved Host-Pathogen Interactions Identify Novel Treatment Options in Betacoronavirus Infections

Signal Transduction and Targeted Therapy, 2021
Soeren Lukassen, Roland Eils
exaly  

Betacoronavirus mRNA vaccine

2020
CIARAMELLA GIUSEPPE, HIMANSU SUNNY
openaire   +4 more sources