Results 21 to 30 of about 44,666 (245)

Broad betacoronavirus neutralization by a stem helix–specific human antibody [PDF]

open access: yesScience, 2021
Targeting a range of betacoranaviruses In the past 20 years, three highly pathogenic β-coronaviruses have crossed from animals to humans, including the most recent: severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A spike protein that decorates these viruses has an S1 domain that binds host cell receptors and an S2 ...
Dora Pinto   +51 more
openaire   +4 more sources

COVID-19: perspectivas terapéuticas en IL-17/Th17

open access: yesIatreia, 2021
Las células T helper-17 (Th17) y la interleuquina (IL) IL-17 desempeñan funciones biológicas relacionadas con la protección contra infecciones por bacterias extracelulares y hongos.
Franky Úsuga-Úsuga   +2 more
doaj   +1 more source

COVID-19: a perspective focus on IL-17/Th17

open access: yesIatreia, 2022
Interleukin 17 (IL-17)-producing helper T cells (Th17) and IL-17 play an important role in the defense against extracellular bacteria and fungi; however, persistent secretion of IL-17 is also an important component in the pathogenesis of many ...
Úsuga-Úsuga, Franky   +2 more
doaj   +1 more source

Multiple Early Introductions of SARS-CoV-2 to Cape Town, South Africa

open access: yesViruses, 2021
Cape Town was the first city in South Africa to experience the full impact of the coronavirus disease 2019 (COVID-19) pandemic. We acquired samples from all suspected cases and their contacts during the first month of the pandemic from Tygerberg Hospital.
Susan Engelbrecht   +8 more
doaj   +1 more source

Development of a Biosensor Based on Angiotensin‐Converting Enzyme II for Severe Acute Respiratory Syndrome Coronavirus 2 Detection in Human Saliva

open access: yesFrontiers in Sensors, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the novel coronavirus responsible for COVID-19. Infection in humans requires angiotensin-converting enzyme II (hACE2) as the point of entry for SARS-CoV-2.
Geisianny Moreira   +11 more
doaj   +1 more source

The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner

open access: yesViruses, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible RNA virus that is the causative agent of the Coronavirus disease 2019 (COVID-19) pandemic.
Victoria Callahan   +14 more
doaj   +1 more source

CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology

open access: yesVaccines, 2021
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain.
Jennifer K. DeMarco   +11 more
doaj   +1 more source

Comparative Study of Blue Light with Ultraviolet (UVC) Radiation on Betacoronavirus 1

open access: yesApplied Sciences, 2023
The ongoing coronavirus pandemic requires more effective disinfection methods. Disinfection using ultraviolet light (UV), especially longer UVC wavelengths, such as 254 and 270/280 nm, has been proven to have virucidal properties, but its adverse effects
Kritika Vashishtha   +3 more
doaj   +1 more source

Bovine Coronavirus: Variability, Evolution, and Dispersal Patterns of a No Longer Neglected Betacoronavirus [PDF]

open access: goldViruses, 2020
Bovine coronavirus (BoCV) is an important pathogen of cattle, causing severe enteric disease and playing a role in the bovine respiratory disease complex. Similar to other coronaviruses, a remarkable variability characterizes both its genome and biology. Despite their potential relevance, different aspects of the evolution of BoCV remain elusive.
Giovanni Franzo   +7 more
openalex   +5 more sources

Postmortem lung and heart examination of COVID-19 patients in a case series from Jordan [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2023
Background Coronavirus disease 2019 (COVID-19) has emerged as a pandemic for more than 2 years. Autopsy examination is an invaluable tool to understand the pathogenesis of emerging infections and their consequent mortalities. The aim of the current study
Maram Abdaljaleel   +10 more
doaj   +1 more source

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