Results 51 to 60 of about 44,666 (245)

Dietary Vitamin D Mitigates Coronavirus-Induced Lung Inflammation and Damage in Mice

Viruses, 2023
The COVID-19 pandemic caused by the SARS-CoV-2 (β-CoV) betacoronavirus has posed a significant threat to global health. Despite the availability of vaccines, the virus continues to spread, and there is a need for alternative strategies to alleviate its ...
Gabriel Campolina-Silva, Ana Cláudia dos Santos Pereira Andrade, Manoela Couto, Paloma G. Bittencourt-Silva, Celso M. Queiroz-Junior, Larisse de Souza B. Lacerda, Ian de Meira Chaves, Leonardo C. de Oliveira, Fernanda Martins Marim, Cleida A. Oliveira, Glauber S. F. da Silva, Mauro Martins Teixeira, Vivian Vasconcelos Costa   +12 more
doaj   +1 more source

Betacoronavirus internal protein: role in immune evasion and viral pathogenesis. [PDF]

J Virol
ABSTRACT Betacoronaviruses express a small internal (I) protein that is encoded by the same subgenomic RNA (sgRNA) as the nucleocapsid (N) protein. Translation of the +1 reading frame of the N sgRNA through leaky ribosomal scanning leads to expression of the I protein.
Gunawardene CD, Wong L-YR.
europepmc   +3 more sources

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]

, 2018
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska, A Pratelli, A Quan, Aleksandra Milewska, AM Zaki, Artur Szczepanski, B Hernaez, B Jancekova, BA Mainou, BJ Dille, C Burkard, C Kooi, C Liu, C Liu, D Dutta, DM Blau, E Dietzel, E Girard, E Hamme Van, EJ Bowman, F Samson, G Preta, GA Wudiri, GM Li, GR Ares, H Imhoff, H Lin, H Wang, IC Huang, IM Mackay, J Li, J Schindelin, J Somsel Rodman, JA Mitchell, JK Millet, JL Wang, JP Lim, JR Henley, Judy A. Mitchell, K Erles, K Erles, K Owczarek, K Shirato, K Shirato, Katarzyna Owczarek, Krzysztof Pyrc, KS Choi, L Kleist von, L Pelkmans, LH Wang, LJ Reed, M Marsh, MG Hemida, MJ Geisow, MJ Vincent, O Achour, O Heikkila, P Duckert, P Eifart, P Oh, Q Xu, R Nomura, S Bertram, S Bolte, S Gierer, S Matsuyama, SL Priestnall, TA Hill, VC Chu, X Ren, Y Inoue, Y Phonphok, Z Qian, Z Qinfen, Zbigniew Baster, Zenon Rajfur   +75 more
core   +7 more sources

Immunodominant antibody responses directed to SARS-CoV-2 hotspot mutation sites and risk of immune escape

Frontiers in Immunology, 2023
IntroductionConsidering the likely need for the development of novel effective vaccines adapted to emerging relevant CoV-2 variants, the increasing knowledge of epitope recognition profile among convalescents and afterwards vaccinated with identification
Jamille Ramos Oliveira, Jamille Ramos Oliveira, Jamille Ramos Oliveira, Cesar Manuel Remuzgo Ruiz, Rafael Rahal Guaragna Machado, Jhosiene Yukari Magawa, Jhosiene Yukari Magawa, Jhosiene Yukari Magawa, Isabela Pazotti Daher, Isabela Pazotti Daher, Isabela Pazotti Daher, Alysson Henrique Urbanski, Gabriela Justamante Händel Schmitz, Gabriela Justamante Händel Schmitz, Helen Andrade Arcuri, Marcelo Alves Ferreira, Greyce Luri Sasahara, Giuliana Xavier de Medeiros, Roberto Carlos Vieira Silva Júnior, Edison Luiz Durigon, Edison Luiz Durigon, Silvia Beatriz Boscardin, Daniela Santoro Rosa, Daniela Santoro Rosa, Deborah Schechtman, Helder I. Nakaya, Helder I. Nakaya, Edecio Cunha-Neto, Edecio Cunha-Neto, Edecio Cunha-Neto, Gabriele Gadermaier, Jorge Kalil, Jorge Kalil, Jorge Kalil, Verônica Coelho, Verônica Coelho, Verônica Coelho, Keity Souza Santos, Keity Souza Santos, Keity Souza Santos   +39 more
doaj   +1 more source

Evaluation of nine serological rapid tests for the detection of SARS-CoV-2

Revista Panamericana de Salud Pública, 2020
Objective. To evaluate the operative capacity of nine serological rapid tests to detect the IgM/IgG antibodies response in serum from patients with SARS-CoV-2 in different clinical stages. Methods.
Marcela Mercado, Jeadran Malagón-Rojas, Gabriela Delgado, Vivian Vanesa Rubio, Lida Muñoz Galindo, Eliana L. Parra Barrera, Paula Gaviria, Gabriela Zabaleta, Zonia Alarcon, Adriana Arévalo, Helly Casallas Cifuentes, Kelly Estrada, Gloria Puerto, María T. Herrera Sepúlveda, Helena Rodríguez, Marisol Galindo, Martha Lucía Ospina Ramírez   +16 more
doaj   +1 more source

Group B Betacoronavirus in Rhinolophid Bats, Japan

Journal of Veterinary Medical Science, 2014
(Uploaded by Plazi for the Bat Literature Project) We report group B Betacoronavirus infection in little Japanese horseshoe bats in Iwate prefecture. We then used reversetranscription PCR to look for the coronavirus RNA-dependent RNA polymerase gene in fecal samples collected from 27 little Japanese horseshoe bats and found eight were provisionally ...
SUZUKI, Jin, SATO, Ryota, KOBAYASHI, Tomoya, AOI, Toshiki, HARASAWA, Ryô   +4 more
openaire   +3 more sources

Conserved Characteristics of NMPylation Activities of Alpha- and Betacoronavirus NiRAN Domains

Journal of Virology, 2023
There is strong evidence that coronaviruses and other large nidoviruses evolved a number of unique enzymatic activities, including an additional RdRp-associated NiRAN domain, that are conserved in nidoviruses but not in most other RNA viruses. Previous studies of the NiRAN domain mainly focused on severe acute respiratory syndrome coronavirus 2 (SARS ...
Heiko Slanina, Ramakanth Madhugiri, Kai Wenk, Tess Reinke, Karin Schultheiß, Julia Schultheis, Nadja Karl, Uwe Linne, John Ziebuhr   +8 more
openaire   +2 more sources

Recombination and Positive Selection Differentially Shaped the Diversity of Betacoronavirus Subgenera [PDF]

Viruses, 2020
The Betacoronavirus genus of mammal-infecting viruses includes three subgenera (Sarbecovirus, Embecovirus, and Merbecovirus), in which most known human coronaviruses, including SARS-CoV-2, cluster. Coronaviruses are prone to host shifts, with recombination and positive selection possibly contributing to their high zoonotic potential.
Forni D, Cagliani R, Sironi M
openaire   +4 more sources

A comparative study of human betacoronavirus spike proteins: structure, function and therapeutics [PDF]

Archives of Virology, 2021
Coronaviruses are the paradigm of emerging 21st century zoonotic viruses, triggering numerous outbreaks and a severe global health crisis. The current COVID-19 pandemic caused by SARS-CoV-2 has affected more than 51 million people across the globe as of 12 November 2020.
Verma, Jyoti, Subbarao, Naidu
openaire   +2 more sources

Polyphyletic origin of MERS coronaviruses and isolation of a novel clade A strain from dromedary camels in the United Arab Emirates [PDF]

, 2016
published_or_final_versio
Chan, KH, Elizabeth, SK, Joseph, S, Kinne, J, Lau, SKP, Muhammed, R, Patteril, NA, Tsang, KL, Wernery, R, Wernery, U, Wong, YM, Woo, PCY, Yuen, KY   +12 more
core   +1 more source