Results 61 to 70 of about 39,409 (160)

A Dual Role of Complement Activation in the Development of Fulminant Hepatic Failure Induced by Murine-Beta-Coronavirus Infection

Frontiers in Cellular and Infection Microbiology, 2022
With the epidemic of betacoronavirus increasing frequently, it poses a great threat to human public health. Therefore, the research on the pathogenic mechanism of betacoronavirus is becoming greatly important. Murine hepatitis virus strain-3 (MHV-3) is a
Yingying Fang, Yingying Fang, Yan Guo, Tongtong Gao, Xuelian Han, Yuting Jiang, Min Li, Wei Xue, Binhui Yang, Yujun Cui, Yujun Cui, Shihui Sun, Guangyu Zhao, Guangyu Zhao   +13 more
doaj   +1 more source

Coverage plot of betacoronavirus reads to coronavirus OC43 reference genome AY391777.1 (depth of coverage: 428).

, 2019
Coverage plot of betacoronavirus reads to coronavirus OC43 reference genome AY391777.1 (depth of coverage: 428).
Marianne Aanerud (318457), Aloys C. M. Kroes (7542383), Ellen C. Carbo (7542371), Igor Sidorov (7329359), Tomas M. Eagan (7392587), Pieter S. Hiemstra (7392584), Anneloes L. van Rijn (7542368), Nikos Pappas (7542374), Mariet Feltkamp (7542377), Eric C. J. Claas (7542380), Sander van Boheemen (187826), Hailiang Mei (3404261), Per Bakke (164964), Jutte J. C. de Vries (7542386)   +13 more
core   +1 more source

Human Coronavirus 229E Uses ORF4/4a to Antagonize the Host Restriction Factor SERINC5

MedComm, Volume 7, Issue 6, June 2026.
The seasonal human coronaviruses 229E and OC43 are common causes of mild respiratory infections but can cause severe disease in vulnerable individuals. Serine incorporator 5 (SERINC5) efficiently inhibits OC43, while hCoV‐229E uses its ORF4/4a accessory proteins to efficiently counteract this restriction by promoting relocalization of SERINC5 to ...
Qinya Xie, Sabrina Noettger, Jan Lawrenz, Sophie Stopper, Susanne Klute, Jan Münch, Dorota Kmiec, Qingxing Wang, Konstantin M. J. Sparrer, Frank Kirchhoff   +9 more
wiley   +1 more source

Dietary Vitamin D Mitigates Coronavirus-Induced Lung Inflammation and Damage in Mice

Viruses, 2023
The COVID-19 pandemic caused by the SARS-CoV-2 (β-CoV) betacoronavirus has posed a significant threat to global health. Despite the availability of vaccines, the virus continues to spread, and there is a need for alternative strategies to alleviate its ...
Gabriel Campolina-Silva, Ana Cláudia dos Santos Pereira Andrade, Manoela Couto, Paloma G. Bittencourt-Silva, Celso M. Queiroz-Junior, Larisse de Souza B. Lacerda, Ian de Meira Chaves, Leonardo C. de Oliveira, Fernanda Martins Marim, Cleida A. Oliveira, Glauber S. F. da Silva, Mauro Martins Teixeira, Vivian Vasconcelos Costa   +12 more
doaj   +1 more source

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, Volume 123, Issue 5, Page 1338-1349, May 2026.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

Evaluation of nine serological rapid tests for the detection of SARS-CoV-2

Revista Panamericana de Salud Pública, 2020
Objective. To evaluate the operative capacity of nine serological rapid tests to detect the IgM/IgG antibodies response in serum from patients with SARS-CoV-2 in different clinical stages. Methods.
Marcela Mercado, Jeadran Malagón-Rojas, Gabriela Delgado, Vivian Vanesa Rubio, Lida Muñoz Galindo, Eliana L. Parra Barrera, Paula Gaviria, Gabriela Zabaleta, Zonia Alarcon, Adriana Arévalo, Helly Casallas Cifuentes, Kelly Estrada, Gloria Puerto, María T. Herrera Sepúlveda, Helena Rodríguez, Marisol Galindo, Martha Lucía Ospina Ramírez   +16 more
doaj   +1 more source

Coronavirus Detection in Bats Captured on the Deforestation Arc of Mato Grosso, Brazil

Zoonoses and Public Health, Volume 73, Issue 3, Page 281-287, May 2026.
ABSTRACT Coronaviruses (CoV) are RNA viruses associated with enteric and respiratory diseases and known for their emergence potential in humans and other mammals. CoVs originate from zoonotic transmission, in which bats are natural reservoirs. Previous studies suggest that CoV diversity is positively correlated with bat diversity, whereas anthropogenic
Matheus Augusto Calvano Cosentino, Victor Wanderkoke, Francimeire Fernandes Ferreira, Sergio Gomes Silva, Mirela D'arc, André Felipe Andrade dos Santos   +5 more
wiley   +1 more source

Betacoronavirus Infection Outbreak, São Paulo, Brazil, Fall 2023

Emerging Infectious Diseases
We report a human coronavirus OC43 infection outbreak in hospitalized patients and healthcare workers in São Paulo, Brazil, occurring after SARS-CoV-2 cases disappeared. Infection was associated with healthcare workers in 5 (29.4%) patients.
Tânia do Socorro Souza Chaves, Ana H. Perosa, Gabriela Barbosa, Diogo B. Ferreira, Nancy Bellei   +4 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source