Results 51 to 60 of about 37,865 (174)

Dietary Vitamin D Mitigates Coronavirus-Induced Lung Inflammation and Damage in Mice

Viruses, 2023
The COVID-19 pandemic caused by the SARS-CoV-2 (β-CoV) betacoronavirus has posed a significant threat to global health. Despite the availability of vaccines, the virus continues to spread, and there is a need for alternative strategies to alleviate its ...
Gabriel Campolina-Silva, Ana Cláudia dos Santos Pereira Andrade, Manoela Couto, Paloma G. Bittencourt-Silva, Celso M. Queiroz-Junior, Larisse de Souza B. Lacerda, Ian de Meira Chaves, Leonardo C. de Oliveira, Fernanda Martins Marim, Cleida A. Oliveira, Glauber S. F. da Silva, Mauro Martins Teixeira, Vivian Vasconcelos Costa   +12 more
doaj   +1 more source

Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins

Biotechnology Progress, EarlyView.
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann, Augustine Duffy, Alex Wee, Noah Anderson, Jackson Terrell, Yoshihiro Kawaoka, Ravi S. Kane   +6 more
wiley   +1 more source

Evaluation of nine serological rapid tests for the detection of SARS-CoV-2

Revista Panamericana de Salud Pública, 2020
Objective. To evaluate the operative capacity of nine serological rapid tests to detect the IgM/IgG antibodies response in serum from patients with SARS-CoV-2 in different clinical stages. Methods.
Marcela Mercado, Jeadran Malagón-Rojas, Gabriela Delgado, Vivian Vanesa Rubio, Lida Muñoz Galindo, Eliana L. Parra Barrera, Paula Gaviria, Gabriela Zabaleta, Zonia Alarcon, Adriana Arévalo, Helly Casallas Cifuentes, Kelly Estrada, Gloria Puerto, María T. Herrera Sepúlveda, Helena Rodríguez, Marisol Galindo, Martha Lucía Ospina Ramírez   +16 more
doaj   +1 more source

Investigation of PDCD1 Gene Polymorphisms and Haplotypes in COVID‐19 Severity and Outcome in a Brazilian Population

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT COVID‐19 severity and survival are influenced by the host immune response to SARS‐CoV‐2. Programmed cell death 1 (PD‐1), a key immune checkpoint, regulates T‐cell activation and antiviral immune balance. Since genetic variability can modulate these responses, we investigated whether the PDCD1 polymorphisms rs11568821 C > T, rs2227982 G > A ...
Sarah Lott Moretto, Pedro Luis Candido de Souza Cassela, Guilherme Lerner Trigo, Marcell Alysson Batisti Lozovoy, Zuleica Naomi Tano, Andrea Name Colado Simão, Karen Brajão de Oliveira   +6 more
wiley   +1 more source

Crystal structure of the membrane (M) protein from a bat betacoronavirus

PNAS Nexus, 2023
Abstract The membrane (M) protein is the most abundant structural protein of coronaviruses including MERS-CoV, SARS-CoV, and SARS-CoV-2, and plays a central role in virus assembly through its interaction with various partner proteins. However, mechanistic details about how M protein interacts with others remain elusive due to lack of ...
Xiaodong Wang, Yuwei Yang, Ziyi Sun, Xiaoming Zhou   +3 more
openaire   +2 more sources

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source

Identification of the Fusion Peptide-Containing Region in Betacoronavirus Spike Glycoproteins [PDF]

Journal of Virology, 2016
ABSTRACT The fusion peptides (FP) play an essential role in fusion of viral envelope with cellular membranes. The location and properties of the FPs in the spike (S) glycoproteins of different coronaviruses (CoV) have not yet been determined. Through amino acid sequence analysis of S proteins of representative CoVs, we identified
Xiuyuan, Ou, Wangliang, Zheng, Yiwei, Shan, Zhixia, Mu, Samuel R, Dominguez, Kathryn V, Holmes, Zhaohui, Qian   +6 more
openaire   +2 more sources

Discovery and characterization of a pan-betacoronavirus S2-binding antibody

Structure
The continued emergence of deadly human coronaviruses from animal reservoirs highlights the need for pan-coronavirus interventions for effective pandemic preparedness. Here, using linking B cell receptor to antigen specificity through sequencing (LIBRA-seq), we report a panel of 50 coronavirus antibodies isolated from human B cells.
Nicole V. Johnson, Steven C. Wall, Kevin J. Kramer, Clinton M. Holt, Sivakumar Periasamy, Simone I. Richardson, Nelia P. Manamela, Naveenchandra Suryadevara, Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giulia Piccini, Ying Huang, Pan Ge, James D. Allen, Naoko Uno, Andrea R. Shiakolas, Kelsey A. Pilewski, Rachel S. Nargi, Rachel E. Sutton, Alexandria A. Abu-Shmais, Robert Parks, Barton F. Haynes, Robert H. Carnahan, James E. Crowe, Emanuele Montomoli, Rino Rappuoli, Alexander Bukreyev, Ted M. Ross, Giuseppe A. Sautto, Jason S. McLellan, Ivelin S. Georgiev   +31 more
openaire   +5 more sources

Canine coronaviruses: emerging and re-emerging pathogens of dogs

Berliner und Münchener Tierärztliche Wochenschrift, 2021
Canine coronavirus (CCoV) and canine respiratory coronavirus (CRCoV) are highly infectious viruses of dogs classified as Alphacoronavirus and Betacoronavirus, respectively.
Ahmed Abd El Wahed, Uwe Truyen
doaj   +1 more source

Assessing the Origin of the COVID19 Pandemic Is Still Important

FASEB BioAdvances, Volume 8, Issue 8, August 2026.
ABSTRACT The COVID19 pandemic, caused by the betacoronavirus SARS‐CoV‐2, now ranks among the world's deadliest plagues, and certainly one of the most significant public health crises in the last 100 years. Despite more than 6 years of investigating the pandemic, it has been difficult to assess the origin of the disease in the City of Wuhan, China.
Jason D. Bannan
wiley   +1 more source