Results 61 to 70 of about 37,714 (159)

Towards Interpreting Zoonotic Potential of Betacoronavirus Sequences With Attention

, 2021
11 pages, 8 figures, 1 table, accepted at ICLR 2021 workshop Machine learning for preventing and combating ...
Wadhawan, Kahini, Das, Payel, Han, Barbara A., Fischhoff, Ilya R., Castellanos, Adrian C., Varsani, Arvind, Varshney, Kush R.   +6 more
openaire   +2 more sources

Os novos paradigmas no tempo de atendimento em pacientes com câncer de cabeça e pescoço durante a pandemia Covid-19: revisão de literatura

Revista da Faculdade de Odontologia de Porto Alegre, 2021
Introdução: O novo coronavirus SARS-CoV2 é uma ameaça de saúde mundial que tem como um de seus principais grupo de risco os pacientes com câncer de cabeça e pescoço. Na atual conjuntura e em caso de uma segunda onda de infecção, há necessidade de um novo
Victor Arthur Rodrigues de Souza, Gabriel Santos Neves, Gustavo Henrique Santos de Almeida, Carlos Eduardo Palanch Repeke   +3 more
doaj   +1 more source

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

Identification of a Novel Betacoronavirus (Merbecovirus) in Amur Hedgehogs from China [PDF]

Viruses, 2019
While dromedaries are the immediate animal source of Middle East Respiratory Syndrome (MERS) epidemic, viruses related to MERS coronavirus (MERS-CoV) have also been found in bats as well as hedgehogs. To elucidate the evolution of MERS-CoV-related viruses and their interspecies transmission pathway, samples were collected from different mammals in ...
Susanna K. P. Lau, Hayes K. H. Luk, Antonio C. P. Wong, Rachel Y. Y. Fan, Carol S. F. Lam, Kenneth S. M. Li, Syed Shakeel Ahmed, Franklin W.N. Chow, Jian-Piao Cai, Xun Zhu, Jasper F. W. Chan, Terrence C. K. Lau, Kaiyuan Cao, Mengfeng Li, Patrick C. Y. Woo, Kwok-Yung Yuen   +15 more
openaire   +3 more sources

Conserved Characteristics of NMPylation Activities of Alpha- and Betacoronavirus NiRAN Domains

Journal of Virology, 2023
There is strong evidence that coronaviruses and other large nidoviruses evolved a number of unique enzymatic activities, including an additional RdRp-associated NiRAN domain, that are conserved in nidoviruses but not in most other RNA viruses. Previous studies of the NiRAN domain mainly focused on severe acute respiratory syndrome coronavirus 2 (SARS ...
Heiko Slanina, Ramakanth Madhugiri, Kai Wenk, Tess Reinke, Karin Schultheiß, Julia Schultheis, Nadja Karl, Uwe Linne, John Ziebuhr   +8 more
openaire   +2 more sources

Coronavirus Detection in Bats Captured on the Deforestation Arc of Mato Grosso, Brazil

Zoonoses and Public Health, EarlyView.
ABSTRACT Coronaviruses (CoV) are RNA viruses associated with enteric and respiratory diseases and known for their emergence potential in humans and other mammals. CoVs originate from zoonotic transmission, in which bats are natural reservoirs. Previous studies suggest that CoV diversity is positively correlated with bat diversity, whereas anthropogenic
Matheus Augusto Calvano Cosentino, Victor Wanderkoke, Francimeire Fernandes Ferreira, Sergio Gomes Silva, Mirela D'arc, André Felipe Andrade dos Santos   +5 more
wiley   +1 more source

A Dual Role of Complement Activation in the Development of Fulminant Hepatic Failure Induced by Murine-Beta-Coronavirus Infection

Frontiers in Cellular and Infection Microbiology, 2022
With the epidemic of betacoronavirus increasing frequently, it poses a great threat to human public health. Therefore, the research on the pathogenic mechanism of betacoronavirus is becoming greatly important. Murine hepatitis virus strain-3 (MHV-3) is a
Yingying Fang, Yingying Fang, Yan Guo, Tongtong Gao, Xuelian Han, Yuting Jiang, Min Li, Wei Xue, Binhui Yang, Yujun Cui, Yujun Cui, Shihui Sun, Guangyu Zhao, Guangyu Zhao   +13 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Dietary Vitamin D Mitigates Coronavirus-Induced Lung Inflammation and Damage in Mice

Viruses, 2023
The COVID-19 pandemic caused by the SARS-CoV-2 (β-CoV) betacoronavirus has posed a significant threat to global health. Despite the availability of vaccines, the virus continues to spread, and there is a need for alternative strategies to alleviate its ...
Gabriel Campolina-Silva, Ana Cláudia dos Santos Pereira Andrade, Manoela Couto, Paloma G. Bittencourt-Silva, Celso M. Queiroz-Junior, Larisse de Souza B. Lacerda, Ian de Meira Chaves, Leonardo C. de Oliveira, Fernanda Martins Marim, Cleida A. Oliveira, Glauber S. F. da Silva, Mauro Martins Teixeira, Vivian Vasconcelos Costa   +12 more
doaj   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source