Results 61 to 70 of about 787 (124)

Metabolomic Biomarkers of Pulmonary Fibrosis in COVID‐19 Patients One Year After Hospital Discharge

open access: yesJournal of Medical Virology, Volume 97, Issue 3, March 2025.
ABSTRACT Coronavirus disease 2019 (COVID‐19) global pandemic has affected more than 600 million people up to date. The symptomatology and severity of COVID‐19 are very broad, and there are still concerns about the long‐term sequelae that it can have on discharged patients.
Marina Botello‐Marabotto   +11 more
wiley   +1 more source

Torsional twist of the SARS‐CoV and SARS‐CoV‐2 SUD‐N and SUD‐M domains

open access: yesProtein Science, Volume 34, Issue 3, March 2025.
Abstract Coronavirus non‐structural protein 3 (nsp3) forms hexameric crowns of pores in the double membrane vesicle that houses the replication–transcription complex. Nsp3 in SARS‐like viruses has three unique domains absent in other coronavirus nsp3 proteins.
Monica Rosas‐Lemus   +13 more
wiley   +1 more source

Investigation of the Blood Microbiome in Horses With Fever of Unknown Origin

open access: yesVeterinary Medicine and Science, Volume 11, Issue 2, March 2025.
ABSTRACT Background Fever of unknown origin (FUO) without a respiratory component is a frequent clinical presentation in horses. Multiple pathogens, both tick‐borne and enteric, can be involved as etiologic agents. An additional potential mechanism is intestinal barrier dysfunction.
Yining Sun   +18 more
wiley   +1 more source

A framework to predict zoonotic hosts under data uncertainty: A case study on betacoronaviruses

open access: yesMethods in Ecology and Evolution, Volume 16, Issue 3, Page 611-624, March 2025.
Abstract Modelling approaches aimed at identifying unknown hosts of zoonotic pathogens have the potential to make high‐impact contributions to global strategies for zoonotic risk surveillance. However, geographical and taxonomic biases in host–pathogen associations affect the reliability of models and their predictions.
Andrea Tonelli   +3 more
wiley   +1 more source

Five‐Year (2017–2022) Evolutionary Dynamics of Human Coronavirus HKU1 in Southern France With Emergence of Viruses Harboring Spike H512R Substitution

open access: yesJournal of Medical Virology, Volume 97, Issue 2, February 2025.
ABSTRACT HCoV‐HKU1 diversity and evolution were scarcely studied. We performed next‐generation sequencing (NGS) and analysis of HCoV‐HKU1 genomes over 5 years. NGS used Illumina technology on NovaSeq 6000 following whole genome PCR amplification by an in‐house set of primers designed using Gemi and PrimalScheme.
Houmadi Hikmat   +9 more
wiley   +1 more source

Novel coronavirus SARS-CoV-2 in the context of global epidemiology of coronavirus infections

open access: yesВестник войск РХБ защиты, 2020
The seemingly unexpected appearance of SARS-CoV-2 in China and its subsequent rapid spread throughout the world make us think seriously about the coronavirus threat emanating from natural foci in the territory of our country.
M. V. Supotnitskiy
doaj   +1 more source

Dynamic Combinatorial Chemistry Unveils Nsp10 Inhibitors with Antiviral Potential Against SARS‐CoV‐2

open access: yesChemistry – A European Journal, Volume 31, Issue 4, January 17, 2025.
This study investigates antiviral strategies targeting SARS‐CoV‐2 by disrupting the protein‐protein interactions of Nsp10 with Nsp14 and Nsp16, which are essential for viral survival. It employs target‐directed dynamic combinatorial chemistry for the identification and synthesis of inhibitors.
Ravindra P. Jumde   +15 more
wiley   +1 more source

Humoral Immunity Profiling to Pandemic and Bat‐Derived Coronavirus Variants: A Geographical Comparison

open access: yesAdvanced Science, Volume 12, Issue 1, January 9, 2025.
Understanding the role of geographic exposure to coronaviruses in the development of cross‐reactive immunity is important for pandemic modeling and interpretation of serology. In this work, the reactivity of U.S. pandemic samples, pre‐pandemic Cambodian samples, and pre‐pandemic U.S.
Parinaz Fathi   +21 more
wiley   +1 more source

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