Results 11 to 20 of about 61,581 (228)

Acute Alcohol Tissue Damage: Protective Properties of Betaine [PDF]

, 2021
Teenage binge drinking is a major health issue; however, there is a paucity of data on liver injury. Herein, we investigated how acute ethanol affects juvenile hepatic cells through changes in oxidative stress, apoptosis, and liver function, as well as ...
Sherwood, Roy A., Patel, V., Petagine, L., Preedy, V.R., Petagine, Lucy, Everitt, H.E., Patel, Vinood B., Patel, V.B., Preedy, Victor R., Everitt, Hannah, Sherwood, R.   +10 more
core   +1 more source

Impact of betaine as a feed additive on livestock performance, carcass characteristics and meat quality- a review [PDF]

SVU-International Journal of Agricultural Sciences, 2019
Betaine (trimethylglycine) is a nontoxic methylamine compound contains the amino acid glycine with three chemically reactive methyl groups. This review gives an overview of the roles of betaine as a feed additive on the performance, carcass, meat quality
M. Abdelsattar, M. Abd El-Ati, A. Hussein, A. Saleem   +3 more
doaj   +1 more source

The betaine content in common cereal-based and gluten-free food from local origin [PDF]

Food and Feed Research, 2015
In this study, betaine content in cereal grains, cereal-based products, gluten-free grains and products of mainly local origin was surveyed. Estimates of betaine are currently a topic of considerable interest. The principal physiologic role of betaine is
Filipčev Bojana V., Brkljača Jovana S., Krulj Jelena A., Bodroža-Solarov Marija I.   +3 more
doaj   +1 more source

Differential regulation of Ota and Otb, two primary glycine betaine transporters in the methanogenic archaeon Methanosarcina mazei go1 [PDF]

, 2008
Methanogenic archaea accumulate glycine betaine in response to hypersalinity, but the regulation of proteins involved, their mechanism of activation and regulation of the corresponding genes are largely unknown.
Schmidt, S., Spanheimer, R., Pflueger, K., Koegl, S., Mueller, V., Hoffmann, M.   +5 more
core   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Multiple deletions of the osmolyte transporters BetL, Gbu, and OpuC of Listeria monocytogenes affect virulence and growth at high osmolarity [PDF]

, 2002
The success of Listeria monocytogenes as a food-borne pathogen owes much to its ability to survive a variety of stresses, both in the food environment and, after ingestion, within the animal host.
Gahan, C.G.M., Wouters, J.A., Abee, T., Hill, C., Wemekamp-Kamphuis, H.H., Sleator, R.D.   +5 more
core   +1 more source

The contrasting relationships between betaine and homocysteine in two clinical cohorts are associated with plasma lipids and drug treatments. [PDF]

PLoS ONE, 2012
BACKGROUND: Urinary betaine excretion positively correlated with plasma homocysteine in outpatients attending a lipid disorders clinic (lipid clinic study). We aimed to confirm this in subjects with established vascular disease.
Michael Lever, Peter M George, Wendy Atkinson, Jane L Elmslie, Sandy Slow, Sarah L Molyneux, Richard W Troughton, A Mark Richards, Christopher M Frampton, Stephen T Chambers   +9 more
doaj   +1 more source

DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. [PDF]

, 2013
BACKGROUND: Animal models show that periconceptional supplementation with folic acid, vitamin B-12, choline, and betaine can induce differences in offspring phenotype mediated by epigenetic changes in DNA. In humans, altered DNA methylation patterns have
Dominguez Salas, Paula, Dyer, Roger A, Andrew M Prentice, Waterland, Robert A., Kerry-Ann da Costa, Cole, Darren, Zeisel, Steven H., Prentice, Andrew M, Hennig, Branwen J, Paula Dominguez-Salas, Sophie E Moore, Moore, Sophie E, Zeisel, Steven H, Anthony JC Fulford, Moore, Sophie E., Robert A Waterland, Darren Cole, Fulford, Anthony JC, Branwen J Hennig, Dyer, Roger A., Fulford, Anthony J.C., Sharon E Cox, Sheila M Innis, Steven H Zeisel, Dominguez-Salas, Paula, Innis, Sheila M, da Costa, Kerry-Ann, Roger A Dyer, Waterland, Robert A, Innis, Sheila M., Cox, Sharon E, Prentice, Andrew M., Da Costa, Kerry Ann, Hennig, Branwen J., Cox, Sharon E.   +34 more
core   +1 more source

Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study

Cardiovascular Diabetology, 2012
Background Since betaine is an osmolyte and methyl donor, and abnormal betaine loss is common in diabetes mellitus (>20% patients), we investigated the relationship between betaine and the post-methionine load rise in homocysteine, in diabetes and ...
Lever Michael, Slow Sandy, McGregor David O, Dellow Warwick J, George Peter M, Chambers Stephen T   +5 more
doaj   +1 more source