Betaine—The dark knight of the brain [PDF]
Basic & Clinical Pharmacology & Toxicology, 2022 AbstractThe role of betaine in the liver and kidney has been well documented, even from the cellular and molecular point of view. Despite literature reporting positive effects of betaine supplementation in Alzheimer's, Parkinson's and schizophrenia, the role and function of betaine in the brain are little studied and reviewed.
Bhatt, Manan +4 more
openaire +3 more sources
Betaine Transport in Kidney and Liver: Use of Betaine in Liver Injury [PDF]
Cellular Physiology and Biochemistry, 2013 Betaine, also known as trimethylglycine, is an important human nutrient obtained from a variety of foods and also can be synthesized from choline. Betaine is much more abundant in kidney and liver compared to other mammalian organs. The principal role of betaine in the kidney is osmoprotection in cells of the medulla and it enters these cells via the ...
Stephen A. Kempson +2 more
openaire +4 more sources
, 2015 Betaine, an important nutritional component for humans, has been reviewed in the synopsis. Its chemical structure, synthesis, utilization and physiological significance have been discussed.
Patel, V., Mehta, K., Patel, V, Mehta, K
openaire +3 more sources
Acute Alcohol Tissue Damage: Protective Properties of Betaine [PDF]
, 2021 Teenage binge drinking is a major health issue; however, there is a paucity of data on liver injury. Herein, we investigated how acute ethanol affects juvenile hepatic cells through changes in oxidative stress, apoptosis, and liver function, as well as ...
Sherwood, Roy A. +10 more
core +1 more source
Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]
, 2011 : Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Moore, SE +4 more
core +5 more sources
The betaine content in common cereal-based and gluten-free food from local origin [PDF]
Food and Feed Research, 2015 In this study, betaine content in cereal grains, cereal-based products, gluten-free grains and products of mainly local origin was surveyed. Estimates of betaine are currently a topic of considerable interest. The principal physiologic role of betaine is
Filipčev Bojana V. +3 more
doaj +1 more source
Differential regulation of Ota and Otb, two primary glycine betaine transporters in the methanogenic archaeon Methanosarcina mazei go1 [PDF]
, 2008 Methanogenic archaea accumulate glycine betaine in response to hypersalinity, but the regulation of proteins involved, their mechanism of activation and regulation of the corresponding genes are largely unknown.
Schmidt, S. +5 more
core +1 more source
Betaine in Cereal Grains and Grain-Based Products
Foods, 2018 Betaine is a non-essential nutrient which performs several important physiological functions in organisms. Abundant data exist to suggest that betaine has a potential for prevention of chronic diseases and that its dietary intake may contribute to ...
Bojana Filipčev +4 more
doaj +1 more source
Multiple deletions of the osmolyte transporters BetL, Gbu, and OpuC of Listeria monocytogenes affect virulence and growth at high osmolarity [PDF]
, 2002 The success of Listeria monocytogenes as a food-borne pathogen owes much to its ability to survive a variety of stresses, both in the food environment and, after ingestion, within the animal host.
Gahan, C.G.M. +5 more
core +1 more source
The contrasting relationships between betaine and homocysteine in two clinical cohorts are associated with plasma lipids and drug treatments. [PDF]
PLoS ONE, 2012 BACKGROUND: Urinary betaine excretion positively correlated with plasma homocysteine in outpatients attending a lipid disorders clinic (lipid clinic study). We aimed to confirm this in subjects with established vascular disease.
Michael Lever +9 more
doaj +1 more source