Results 51 to 60 of about 6,442 (216)

BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT

Frontiers in Immunology, 2019
A recent approach for limiting production of pro-inflammatory cytokines has been to target bromodomain and extra-terminal (BET) proteins. These epigenetic readers of histone acetylation regulate transcription of genes involved in inflammation ...
Sabrina N. Copsel, Sabrina N. Copsel, Casey O. Lightbourn, Henry Barreras, Ines Lohse, Ines Lohse, Dietlinde Wolf, Cameron S. Bader, John Manov, Brandon J. Kale, Devangi Shah, Shaun P. Brothers, Shaun P. Brothers, Victor L. Perez, Krishna V. Komanduri, Krishna V. Komanduri, Krishna V. Komanduri, Claes Wahlestedt, Claes Wahlestedt, Robert B. Levy, Robert B. Levy, Robert B. Levy, Robert B. Levy   +22 more
doaj   +1 more source

Maternal autonomy, caste system, and children's school enrollment in India

Family Relations, Volume 75, Issue 1, Page 619-642, February 2026.
Abstract Objective This study examined the relationship between maternal autonomy and children's school enrollment in India and assessed how caste‐based social stratification moderates this association. Background Maternal autonomy, encompassing financial control, decision‐making power, and mobility are key determinants of child development.
Poulami Chatterjee, Saikat Ghosh, Lahari Chakraborty   +2 more
wiley   +1 more source

Preclinical Studies Support Combined Inhibition of BET Family Proteins and Histone Deacetylases as Epigenetic Therapy for Cutaneous T-Cell Lymphoma

Neoplasia: An International Journal for Oncology Research, 2019
Advanced-stage cutaneous T-cell lymphoma (CTCL) is usually a fatal malignancy despite optimal use of currently available treatments. In this preclinical study of novel CTCL therapy, we performed in vitro and ex vivo experiments to determine the efficacy ...
Lei Zhao, Jean-Phillip Okhovat, Eric K. Hong, Youn H. Kim, Gary S. Wood   +4 more
doaj   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

A matter of salt: Global assessment of the effect of salt ionic composition as a driver of aquatic bacterial diversity

Limnology and Oceanography Letters, Volume 11, Issue 1, January 2026.
Abstract While the influence of salinity on microbial diversity is well documented in marine and brackish ecosystems, the impact of different dissolved inorganic ion types remains largely unexplored. In this study, we assessed how ionic composition shapes planktonic bacterial community structure in inland saline aquatic habitats, compared to the ...
Attila Szabó, Anna J. Székely, Emil Boros, Zsuzsanna Márton, Bianka Csitári, Natalie Barteneva, Dóra Anda, Péter Dobosy, Alexander Eiler, Stefan Bertilsson, Tamás Felföldi   +10 more
wiley   +1 more source

Bat Hunting, Illness, and Health‐Seeking Behavior Among a Bat‐Hunter Community in Bangladesh: Biomedical Versus Local Views

Advances in Public Health, Volume 2026, Issue 1, 2026.
This study explores socioeconomic and health‐related aspects of a bat‐hunter community in Bangladesh, focusing on their unique cultural practices and the associated risks of bat‐borne infections. The hunter community predominantly engages in day labor and seasonal bat hunting as supplementary income.
A. K. M. Dawlat Khan, Hannah Wesley
wiley   +1 more source

Son preference, security concerns and crime against women: Expanding the public health discourse in India

Indian Journal of Public Health, 2020
The phenomenon of son preference in India and the declining number of girls due to such a mindset has been an area of concern. While the Preconception and Prenatal Diagnostic Techniques Act and the Beti Bachao and Beti Padhao scheme have been the ...
Bijayalaxmi Nanda, Nupur Ray, Ritwika Mukherjee   +2 more
doaj   +1 more source

Genetic Diversity of Theileria parva and Anaplasma spp. Isolated From Ticks Collected From Kiambu County, Kenya

BioMed Research International, Volume 2026, Issue 1, 2026.
Environmental changes and human activities such as deforestation and expansion of agricultural land are increasing tick‐borne diseases including Anaplasmosis, Babesiosis, Ehrlichiosis, and Theileriosis. These diseases, which affect animals, can be transmitted to humans through tick bites.
Peter Gichuki, Caroline Wasonga, Christine Adhiambo, Joel Lutomiah, Poorani Gurumallesh Prabu   +4 more
wiley   +1 more source

Beti Bachao Beti Padhao Scheme: A March towards Gender Equality and Women Empowerment

International Journal For Multidisciplinary Research, 2023
The gender equality in terms of survival and education is essential for equitable economic development of any nation and is a basic human right. In Indian Patriarchal society, gender discrimination is deeply rooted which can be seen even in the form of female foeticide due to preference of son over daughter.
openaire   +1 more source

Mongo Beti and Liberty: A Study of His and Other Names in his Fiction

, 2015
The primary concern of this paper is to argue that Mongo Beti is very political in his search for liberty in the choice of his pseudonyms the names of some of his major characters and consequently his fiction Before he discovered the hypocrisy in the
Henry K. Jick, Andrew Tata Ngeh
core