Results 111 to 120 of about 136,011 (340)

Optimal control of cytotoxic and antiangiogenic therapies on prostate cancer growth [PDF]

arXiv, 2020
Prostate cancer can be lethal in advanced stages, for which chemotherapy may become the only viable therapeutic option. While there is no clear clinical management strategy fitting all patients, cytotoxic chemotherapy with docetaxel is currently regarded as the gold standard.
arxiv  

Intracameral Injection of Bevacizumab for the Treatment of Neovascular Glaucoma [PDF]

, 2011
Purpose: To assess the duration of the effect of intracameral bevacizumab in patients presenting with rubeosis iridis and neovascular glaucoma (NVG). Methods: Retrospective analysis of 24 consecutive eyes of 24 patients with decompensated NVG (> 21 mm Hg)
Haritoglou, Christos, Jagow, Burkhard von, Ulbig, Michael, Wolf, Armin   +3 more
core   +1 more source

Final Overall Survival of a Randomized Trial of Bevacizumab for Primary Treatment of Ovarian Cancer.

Journal of Clinical Oncology, 2019
PURPOSE We report the final, protocol-specified analysis of overall survival (OS) in GOG-0218, a phase III, randomized trial of bevacizumab in women with newly diagnosed ovarian, fallopian tube, or primary peritoneal carcinoma. METHODS A total of 1,873
K. Tewari, R. Burger, Danielle M. Enserro, B. Norquist, E. Swisher, M. Brady, M. Bookman, G. Fleming, Helen Q. Huang, H. Homesley, J. Fowler, B. Greer, M. Boente, S. Liang, C. Ye, C. Bais, L. Randall, J. Chan, J. Ferriss, R. L. Coleman, C. Aghajanian, T. Herzog, P. Disaia, L. Copeland, R. Mannel, M. Birrer, B. Monk   +26 more
semanticscholar   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Systemic Use of Bevacizumab for Recurrent Respiratory Papillomatosis: Who, What, Where, When, and Why?

, 2023
The Laryngoscope, Volume 133, Issue 1, Page 2-3, January 2023.
Craig S. Derkay, Emily E. Wikner, Seth Pransky, Simon R. Best, Karen Zur, Douglas R. Sidell, Adam Klein, Clark Rosen, Frederick G. Dikkers, Romaine Johnson   +9 more
wiley   +1 more source

Efferent therapy in the first-line drug treatment of metastatic colorectal cancer

Медицинский совет, 2018
The aim of this study is to analyse the efficacy of efferent therapy (hemosorption) as part of drug treatment in patients with metastatic colorectal cancer (mCRC) based on the use of standard first-line chemotherapy combined with the bevacizumab ...
Z. S. Kotova, T. Yu. Semiglazova, I. A. Baldueva, D. H. Latipova, D. O. Yurlov, V. V. Semiglazov, G. M. Teletaeva, A. V. Novik, A. I. Semenova, S. A. Protsenko   +9 more
doaj   +1 more source

IMbrave 050: a Phase III trial of atezolizumab plus bevacizumab in high-risk hepatocellular carcinoma after curative resection or ablation.

Future Oncology, 2020
Hepatocellular carcinoma recurs in 70-80% of cases following potentially curative resection or ablation and the immune component of the liver microenvironment plays a key role in recurrence.
S. Hack, J. Spahn, Minshan Chen, A. Cheng, A. Kaseb, M. Kudo, H. Lee, A. Yopp, P. Chow, S. Qin   +9 more
semanticscholar   +1 more source

Tumoroid Model Reveals Synergistic Impairment of Metabolism by Iron Chelators and Temozolomide in Chemo‐Resistant Patient‐derived Glioblastoma Cells

Advanced Science, EarlyView.
This study investigates the metabolic vulnerabilities of glioblastoma (GBM), an aggressive brain tumor. Research demonstrates that iron chelation therapy, in combination with standard chemotherapy, significantly enhances the efficacy of treatment against resistant GBM cells in a 3D tumoroid model.
Meitham Amereh, Amir Seyfoori, Shahla Shojaei, Sarah Lane, Tian Zhao, Mahdieh Shokrollahi Barough, Julian J. Lum, Patrick Walter, Mohsen Akbari   +8 more
wiley   +1 more source

Thymoquinone induces apoptosis in temozolomide‐resistant glioblastoma cells via the p38 mitogen‐activated protein kinase signaling pathway

Environmental Toxicology, Volume 38, Issue 1, Page 90-100, January 2023., 2023
Abstract Temozolomide (TMZ) can cross the blood‐brain barrier (BBB) and deliver methyl groups to the purine (guanine) bases of DNA, leading to mispairing during DNA replication and subsequent cell death. However, increased expression of the repair enzyme methyl guanine methyltransferase (MGMT), which removes methyl groups from purine bases, counteracts
Ai Mai, Shu‐Wen Ye, Jia‐Yu Tu, Jun Gao, Zhan‐Fang Kang, Qian‐Ming Yao, Wei‐Jen Ting   +6 more
wiley   +1 more source

Gravity influences bevacizumab distribution in an undisturbed balanced salt solution in vitro.

PLoS ONE, 2019
PurposeThe effects of gravity on bevacizumab or the recommended head position after intraocular bevacizumab injection have not been reported. To evaluate the effect of gravity on bevacizumab in vitro, we added bevacizumab to the upper part of a test tube
Rae Young Kim, Soonil Kwon, Ho Ra
doaj   +1 more source