Methods of multi-indication meta-analysis for health technology assessment: a simulation study [PDF]
A growing number of oncology treatments, such as bevacizumab, are used across multiple indications. However, in health technology assessment (HTA), their clinical and cost-effectiveness are typically appraised within a single target indication. This approach excludes a broader evidence base across other indications.
arxiv
Bevacizumab in combination chemotherapy for colorectal and other cancers [PDF]
Susannah E. Motl
openalex +1 more source
Optic Nerve Sheath Meningiomas in Children: Diagnostic Challenges Based on a Case Series
ABSTRACT The diagnosis of optic nerve sheath meningiomas (ONSM) in children and teenagers remains challenging despite advances in high‐quality imaging. We identified seven children diagnosed with ONSM in four tertiary paediatric oncology centres in the United Kingdom.
Deysha Ratnasingham+15 more
wiley +1 more source
Bevacizumab Plus Fluorouracil: The Value of Being Part of a Developing Story [PDF]
Alberto Sobrero, Paolo Bruzzi
openalex +1 more source
Short‐term effects of fresh mother's own milk in very preterm infants
Abstract Fresh mother's own milk (MOM) can protect preterm infants from many complications. Often MOM is pasteurized for safety, which can deactivate cellular and bioactive components with protective benefits. Questions remain regarding whether pasteurized MOM provides the same benefits as fresh MOM.
Jing Huang+6 more
wiley +1 more source
Addition of Bevacizumab to Bolus Fluorouracil and Leucovorin in First-Line Metastatic Colorectal Cancer: Results of a Randomized Phase II Trial [PDF]
Fairooz F. Kabbinavar+9 more
openalex +1 more source
Recent progress on nanotechnologies for enhancing blood‐brain barrier permeability
In this review, we summarize innovative strategies for harnessing the power of nanotechnology to enhance blood‐brain barrier permeability, a key challenge for central nervous system (CNS) drug delivery. We overview structural innovation of nanocarriers, improvements in targeting strategies, and nanotechnology‐enhanced brain imaging.
Qibin Liu+4 more
wiley +1 more source
Bevacizumab in the therapy for refractory metastatic colorectal cancer
Mary F MulcahyNorthwestern University, Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Chicago IL, USAAbstract: Colorectal cancer is the second most common cause of cancer related deaths in the United States.
Mary F Mulcahy
doaj
Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri+11 more
wiley +1 more source