Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Esophageal perforation in a patient with lung cancer after administration of bevacizumab combined with radiotherapy and chemotherapy: A case report. [PDF]
Jia Q, Zhou YL, Duan LY, Li HC, Hu G.
europepmc +1 more source
Recent developments in eosinophilic renal neoplasms: what's new, true and important?
Recent developments and acquired knowledge on newer renal entities with eosinophilic cytoplasm opened insights into the clinical, pathological, immunohistochemical, molecular, epidemiological aspects, and the prognosis of these entities. We emphasize the role of routine morphology, aided by appropriate and select immunohistochemistry, as essential keys
Kiril Trpkov +2 more
wiley +1 more source
Role of Angiogenesis in Retinal Diseases and New Advances in Drug Development. [PDF]
Boey E, Zaidi H, Tang T, Yazdanyar A.
europepmc +1 more source
In this review, we summarise the major recent advances in Testicular Sex Cord‐Stromal Tumours, focusing on molecular alterations and biomarkers relevant for diagnosis, classification and prognosis. Testicular sex cord‐stromal tumours (TSCSTs) represent ~4%–8% of all testicular neoplasms.
João Lobo, Andres M Acosta
wiley +1 more source
ABSTRACT Background & Aims Despite the advances in systemic therapy for unresectable hepatocellular carcinoma (HCC), patients with Child–Pugh class B (CP‐B) liver function face a significant unmet need. This study evaluated the efficacy and safety of atezolizumab plus bevacizumab (Atez/Bev) in patients with unresectable HCC and CP‐B.
Ryu Sasaki +25 more
wiley +1 more source
Aflibercept, ranibizumab, and bevacizumab for macular neovascularization secondary to age-related macular degeneration: a retrospective OCT-angiography study. [PDF]
Lombardo M +6 more
europepmc +1 more source
Macular OCT findings in ROP patients treated with both laser and bevacizumab
Cristina Santos +4 more
openalex +1 more source
Clinical Efficacy and Safety of Intralesional Bevacizumab in Dermatology: Insights from a Systematic Review. [PDF]
Rastegarnasab F +5 more
europepmc +1 more source

