Results 121 to 130 of about 2,336,278 (343)

Coherent Elastic Neutrino-Nucleus Scattering as a Precision Test for the Standard Model and Beyond: The COHERENT Proposal Case

Advances in High Energy Physics, 2019
Several experimental proposals expect to confirm the recent measurement of the coherent elastic neutrino-nucleus scattering (CEvNS). Motivated in particular by the next generation experiments of the COHERENT collaboration, we study their sensitivity to ...
O. Miranda, G. Sanchez Garcia, O. Sanders   +2 more
semanticscholar   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Detecting dark matter with Aharonov-Bohm

Journal of High Energy Physics, 2019
While the evidence for dark matter continues to grow, the nature of dark matter remains a mystery. A dark U(1) D gauge theory can have a small kinetic mixing with the visible photon which provides a portal to the dark sector.
John Terning, Christopher B. Verhaaren
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Baryogenesis, dark matter, and flavor structure in non-thermal moduli cosmology

Journal of High Energy Physics, 2019
The appearance of scalar/moduli fields in the early universe, as motivated by string theory, naturally leads to non-thermal “moduli cosmology”. Such cosmology provides a consistent framework where the generation of radiation, baryons, and dark matter can
Mu-Chun Chen, Volodymyr Takhistov
doaj   +1 more source

Beyond the Standard Model at HERA

, 2007
The prospects of physics beyond the standard model in deep inelastic scattering are reviewed, emphasizing the search for contact interactions, for leptoquarks and for supersymmetry with R-parity violation. R-parity violating supersymmetry is explored as a speculative source of events with high energy muons and missing transverse momentum, but no ...
openaire   +4 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Anatomy of beyond the standard model

, 2019
We present for the first time a model-independent anatomy of the ratio in the context of the effective theory with operators invariant under QCD and QED and in the context of the standard model effective field theory (SMEFT) with the operators invariant ...
Jason Aebischer, C. Bobeth, A. Buras, D. Straub   +3 more
semanticscholar   +1 more source

Beyond the Standard Model

, 2018
I present a brief outline of some of the different paths for extending the Standard Model. These include supersymmetry, Grand Unified Theories, extra dimensions, and multi-Higgs models. The aim is to give graduate students an overview of some of the theoretical motivations to go into a specific extension, and a few examples of how the experimental ...
openaire   +2 more sources