Results 171 to 180 of about 85,869 (275)

碱性成纤维生长因子对脂肪干细胞分化为心肌细胞的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2015
摘 要: 【目的】 探讨碱性成纤维生长因子(bFGF)对脂肪干细胞(ADSC)分化为心肌细胞的影响?【方法】 从SD大鼠中提取?分离?培养?鉴定ADSC后,评价ADSC分化能力?将成功建立心肌梗死(MI)模型的60只大鼠随机分4组(n = 15/组):PBS组?bFGF组?ADSC组及bFGF+ADSC组?建立心梗1周后分别注射PBS?bFGF?ADSC及bFGF+ADSC,4周后用心脏超声测量心梗大鼠的左室射血分数(EF),取大鼠心脏检测左室梗死面积?微血管密度(MVD)及ADSC分化?【结果 ...
doaj  

Maternal obesity induces activator protein 1‐mediated inflammatory response to impair embryonic neurogenesis

The Journal of Physiology, EarlyView.
Abstract figure legend Maternal obesity (MO) creates a pro‐inflammatory embryonic environment, which activates the activator protein 1 (AP‐1) transcription factor complex, resulting in reduced expression of key neurogenic regulators and impaired neuronal differentiation.
Li‐Wei Chen, Md Nazmul Hossain, Yao Gao, Zhongyun Kou, Sharmeen Islam, Xinrui Li, Chaeyoung Shin, Jeanene Marie de Avila, Mei‐Jun Zhu, Min Du   +9 more
wiley   +1 more source

Glycosaminoglycan-Inspired Polymer Brushes Promote Human Mesenchymal Stem Cell Proliferation While Retaining Trilineage Differentiation Potential. [PDF]

ACS Appl Mater Interfaces
Nelson CL, Castellion CA, Humpal AP, Sekar RP, Chaudhary N, Villa-Diaz LG, Kumar R.   +6 more
europepmc   +1 more source

PEX基因在肿瘤细胞中的表达及其体外对微血管生成的影响

Zhongguo shiyan zhenduanxue, 2010
目的探讨PEX基因在体外对微血管生成的影响。方法利用RT-PCR、人脐静脉内皮细胞(HUVEC)小管形成实验及鸡胚绒毛尿囊膜(CAM)血管形成实验,体外观察PEX基因对血管生成的影响。结果稳定筛选的细胞株BpcDNA-sPEX经RT-PCR可扩增出sPEX带;bFGF+BpcDNA-sPEX组小管数明显少于bFGF+BpcDNA、bFGF+B16F10组 ...
doaj  

Wnt5a‐Induced Exosomes From Bone Marrow Mesenchymal Stem Cells Promote Spinal Cord Injury Repair by Modulating Immune Cell Phenotypes and Alleviating Neuroinflammation via the NF‐κB Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Wnt5a positively influences neuronal regeneration after SCI via BMSC‐Exos, potentially through immune regulation and suppression of neuroinflammation. Transplantation of Wnt5a‐modified BMSC‐Exos could enhance tissue repair and the recovery of motor function after SCI in vivo, highlighting their potential in treating SCI.
Dan Luo, Enhui Feng, Ling Chen, Ke Ni, Sheng Luo, Lin Ma, Yuting Wu, Zhifeng Hu, Dingkun Lin, Binshan Zhang, Chaoyi Yin, Da Guo, Chaolun Liang, Xing Li   +13 more
wiley   +1 more source

An Overview of the Mechanisms of Fractional CO₂ Laser in Scar Treatment. [PDF]

Lasers Med Sci
Zhang L, Liu C, Li L.
europepmc   +1 more source

Single‐Cell RNA‐Sequencing Reveals Cachectic Satellite Cell Population in Muscle of Male Mice With Cancer Cachexia

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Cancer cachexia leads to decreases in body mass, lean mass and fat mass, decreased therapeutic potential and ~20% of cancer‐related deaths. While several studies have demonstrated changes to components of the muscle microenvironment with cancer cachexia, none have comprehensively assessed changes to cellular dynamics across the ...
Alex Brown, Nicolás Collao, Aisha Saleh, Natasha Strong, Michael De Lisio, Nadine Wiper‐Bergeron   +5 more
wiley   +1 more source

Basic fibroblast growth factor (bFGF) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

P-LM421E8, the heparan sulfate chain-conjugated laminin-421-E8 fragment, drives differentiation of human induced pluripotent stem cells into hematopoietic progenitor cells comparable to basic fibroblast growth factor in a chemically defined system. [PDF]

Matrix Biol Plus
Ninomiya N, Sasaki K, Katori R, Shimizu Y, Fujita K, Taniguchi Y, Kunieda T, Tamura K, Yamada M, Sekiguchi K, Kimura H.   +10 more
europepmc   +1 more source

NDUFS1‐Mediated Mitochondrial Complex I Activity Maintains Pancreatic Cancer Stemness by Promoting PAX2 Hypomethylation

MedComm, Volume 7, Issue 4, April 2026.
Pancreatic cancer stem cells (CSCs) maintain stemness and tumorigenicity through NDUFS1‐mediated complex I activity, which is transcriptionally upregulated via the CD147‐STAT3 signaling axis. Enhanced oxidative phosphorylation (OXPHOS) and NAD+ production driven by this CD147‐NDUFS1 axis subsequently trigger the SIRT1‐DNMT1 metaboloepigenetic signaling
Xin‐Yu Fan, Wen Li, Ying Shi, Bao‐Qing Xu, Hao Wang, Ruo‐Fei Tian, Zi‐Chuan Duan, Jing Fan, Jia‐Rong Liu, Xiu‐Xuan Sun, Bin Wang, Li‐Juan Wang, Ke Wang, Shi‐Jie Wang, Xiang‐Min Yang, Hong‐Yong Cui, Zhi‐Nan Chen, Ling Li   +17 more
wiley   +1 more source