Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
ABSTRACT In plants, iron homeostasis and oxygen metabolism are strictly related, indeed several Fe‐requiring enzymes catalyze reactions that also involve O2 as a reagent, product, entry or end point of the pathway. Oxygen sensing itself relies on the Fe‐dependent enzymes Plant cysteine oxidases.
Yuri Telara +9 more
wiley +1 more source
Unraveling the genetic and molecular mechanisms of anthocyanin biosynthesis and accumulation in maize kernels. [PDF]
He M, Li J, Jin W, Liu J.
europepmc +1 more source
Untersuchungen zur Rolle der MYB- und BHLH-Proteine in der Regulation der indolischen Glukosinolatbiosynthese [PDF]
Frerigmann, Henning
core
Klhl31 is assocaited with skeletal myogenesis and its expression is regulated by myogenic signals and Myf-5 [PDF]
Adams +42 more
core +1 more source
ABSTRACT Multigenerational stress exposure induces stress memory in plants, influencing resource allocation, defence mechanisms, and productivity. Weed competition imposes both resource‐based (abiotic) and allelopathic (biotic) stress, engaging overlapping hormonal pathways.
Albert O. Kwarteng +4 more
wiley +1 more source
Genome-wide identification and expression profiling of bHLH transcription factors associated with ferulic acid biosynthesis in <i>Angelica sinensis</i>. [PDF]
Arshad KT +5 more
europepmc +1 more source
The E3 Ligase RNF8 Promotes Ubiquitination and Degradation of ChREBPα During Liver Stress Response
During MASH development, increasing hepatic stress signals, particularly a combination of lipotoxicity (palmitate) and inflammation (TNFα), trigger JNK, the key stress‐activated protein kinase. Activated JNK recruits RNF8, a stress‐induced E3 ligase, to promote ubiquitination and proteasomal degradation of the ChREBPα protein.
Yuee Zhao +8 more
wiley +1 more source
Better together: the transcription factor MUTE aggregates into nuclear condensates to regulate stomatal development in maize. [PDF]
González-Suárez P.
europepmc +1 more source
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben +4 more
wiley +1 more source

