Results 11 to 20 of about 72,341 (282)
Evolution of A bHLH Interaction Motif [PDF]
International Journal of Molecular Sciences, 2021 Intrinsically disordered proteins and regions with their associated short linear motifs play key roles in transcriptional regulation. The disordered MYC-interaction motif (MIM) mediates interactions between MYC and MYB transcription factors in Arabidopsis thaliana that are critical for constitutive and induced glucosinolate (GLS) biosynthesis.
Peter S. Millard +2 more
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Prokineticin 2 Is a Target Gene of Proneural Basic Helix-Loop-Helix Factors for Olfactory Bulb Neurogenesis [PDF]
, 2007 Prokineticin 2, a cysteine-rich secreted protein, regulates diverse biological functions including the neurogenesis of olfactory bulb. Here we show that the PK2 gene is a functional target gene of proneural basic helix-loop-helix (bHLH) factors ...
Anderson, David J. +6 more
core +1 more source
The bHLH network underlying plant shade‐avoidance [PDF]
Physiologia Plantarum, 2020 Shade is a potential threat to many plant species. When shade‐intolerant plants detect neighbours, they elongate their stems and leaves in an effort to maximise their light capture. This developmental programme, known as ‘shade‐avoidance’ is tightly controlled by specialised photoreceptors and a suite of transcriptional regulators. The basic helix–loop–
Buti, Sara, Hayes, Scott, Pierik, Ronald
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Automatic annotation of the bHLH gene family in plants
BMC Genomics, 2023 Background The bHLH transcription factor family is named after the basic helix-loop-helix (bHLH) domain that is a characteristic element of their members. Understanding the function and characteristics of this family is important for the examination of a
Corinna Thoben, Boas Pucker
doaj +1 more source
Mechanisms of Binding Specificity among bHLH Transcription Factors [PDF]
International Journal of Molecular Sciences, 2021 The transcriptome of every cell is orchestrated by the complex network of interaction between transcription factors (TFs) and their binding sites on DNA. Disruption of this network can result in many forms of organism malfunction but also can be the substrate of positive natural selection.
Xabier de Martin +2 more
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Biotechnology & Biotechnological Equipment, 2020 Red-fleshed pummelo (Citrus grandis), a mutant of ‘Guanxi’, is an important economic plant rich in carotenoids. The transcriptome of ‘Guanxi’ pummelo was compared with red-fleshed pummelo, with the aim of identifying the key genes responsible for red ...
Dongxia Wang +5 more
doaj +1 more source
Context dependence of proneural bHLH proteins [PDF]
Current Opinion in Genetics & Development, 2008 A key point in neural development is the commitment of progenitor cells to a specific neural fate. In all animals studied, proneural proteins - transcription factors of the basic helix-loop-helix (bHLH) family - are central to this process. The function of these factors is strongly influenced by the spatial and temporal context in which they are ...
Powell, Lynn M., Jarman, Andrew P.
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DNA bending by bHLH charge variants [PDF]
Nucleic Acids Research, 2006 We wish to understand the role of electrostatics in DNA stiffness and bending. The DNA charge collapse model suggests that mutual electrostatic repulsions between neighboring phosphates significantly contribute to DNA stiffness. According to this model, placement of fixed charges near the negatively charged DNA surface should induce bending through ...
McDonald, Robert J. +2 more
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A bHLH Code for Cardiac Morphogenesis [PDF]
Pediatric Cardiology, 2009 Cell specification and differentiation of cardiomyocytes from mesodermal precursors is orchestrated by epigenetic and transcriptional inputs throughout heart formation. Of the many transcription factor super families that play a role in this process, the basic Helix-loop Helix (bHLH) family of proteins is well represented.
Simon J, Conway +2 more
openaire +2 more sources
A seed-specific regulator of triterpene saponin biosynthesis in Medicago truncatula [PDF]
, 2020 Plants produce a vast array of defense compounds to protect themselves from pathogen attack or herbivore predation. Saponins are a specific class of defense compounds comprising bioactive glycosides with a steroidal or triterpenoid aglycone backbone. The
Arendt, Philipp +11 more
core +2 more sources