Results 41 to 50 of about 1,685,795 (292)

BI-3406, a potent and selective SOS1::KRAS interaction inhibitor, is effective in KRAS-driven cancers through combined MEK inhibition

Cancer Discovery, 2020
KRAS is the most frequently mutated driver of pancreatic, colorectal, and non-small cell lung cancers. Direct KRAS blockade has proven challenging and inhibition of a key downstream effector pathway, the RAF-MEK-ERK cascade, has shown limited success due
M. H. Hofmann, M. Gmachl, J. Ramharter, F. Savarese, D. Gerlach, J. Marszalek, M. Sanderson, D. Kessler, F. Trapani, Heribert Arnhof, K. Rumpel, Dana-Adriana Botesteanu, P. Ettmayer, Thomas Gerstberger, C. Kofink, Tobias Wunberg, A. Zoephel, Szu-Chin Fu, Jessica L. F. Teh, Jark Böttcher, Nikolai Pototschnig, Franziska Schachinger, Katharina Schipany, Simone Lieb, C. Vellano, J. C. O'Connell, Rachel L. Mendes, J. Moll, M. Petronczki, T. Heffernan, M. Pearson, D. McConnell, N. Kraut   +32 more
semanticscholar   +1 more source

Development of a method of continuous improvement of services using the Business Intelligence tools

Открытое образование (Москва), 2018
The purpose of the study was to develop a method of continuous improvement of services using the Business Intelligence tools.Materials and methods: the materials are used on the concept of the Deming Cycle, methods and Business Intelligence technologies,
Svetlana V. Kulikova, Alexander A. Kruglov   +1 more
doaj   +1 more source

Determination of As, Sb and Bi in Soil and Stream Sediment by a Self-developed Hydride Generation System Coupled with Inductively Coupled Plasma-Optical Emission Spectrometry

Yankuang ceshi, 2015
Hydride Generation (HG) combined with Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES) has excellent analytical sensitivity. However, the instable chemical reactions of HG may cause unsatisfactory analytical precision.
WU Zheng, XIONG Ying, WANG Long-shan
doaj   +1 more source

Community integration of people with nonheterosexual identities in Indian society: An integrated and intersectional approach

Indian Journal of Social Psychiatry, 2018
This article adopts a multidisciplinary approach to community integration (CI). We concentrate on CI programs for sexual minorities. Stakeholders are those nonheterosexual individuals who experience psychological distress when confronted by social ...
Vinod Kumar Sinha, Kathinka Sinha-Kerkhoff   +1 more
doaj   +1 more source

Performance study of self-supported Bi catalysts regulated by electrodeposition for electrochemical CO2 reduction to formate

工程科学学报
This study developed a high-performance electrocatalyst for the electrochemical reduction of CO2 to formate, thereby promoting CO2 resource utilization and contributing to carbon neutrality. A self-supported bismuth (Bi) metal catalyst was fabricated via
Jianhe LIU, Tao YANG, Yuanbo CAO, Liming YANG, Xinmei HOU   +4 more
doaj   +1 more source

Learning to Monitor Machine Health with Convolutional Bi-Directional LSTM Networks

Italian National Conference on Sensors, 2017
In modern manufacturing systems and industries, more and more research efforts have been made in developing effective machine health monitoring systems. Among various machine health monitoring approaches, data-driven methods are gaining in popularity due
Rui Zhao, Ru-Qiang Yan, Jinjiang Wang, Kezhi Mao   +3 more
semanticscholar   +1 more source

Bi-weekly average new, infected, recovered, deceased cases in India (March 14 –November 5, 2020).

, 2021
(a). Bi-weekly average new cases; (b). Bi-weekly average infected cases bi-weekly; (c). Bi-weekly average recovered cases; (d). Bi-weekly average deceased cases.
Vandana Tamrakar (11506943), Apala Saha (11506952), Benjamin Debbarma (11506955), Nandita Saikia (822178), Mukesh C. Parmar (11506946), Ankita Srivastava (25789), Shewli Shabnam (11506949), Bandita Boro (9499435), Sudheer Kumar Shukla (10737825)   +8 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Metalliferous jurassic rocks of the Fan-Y agnob syneclise (Central Tajikistan)

Известия высших учебных заведений: Геология и разведка
Background. The Fan-Yagnob syneclise is an imposed structure within the Hercynian Zeravshan-Gissar zone. It formed on a Paleozoic folded basement as series of sedimentary rocks from T3 to N1, including Jurassic, Cretaceous, and Paleogene terrigenous ...
M. Saymudasiri, A. K. Litvinenko
doaj   +1 more source