Results 51 to 60 of about 4,343,741 (269)

Aborder la mort à l'école primaire [PDF]

open access: yes, 2014
La mort est un sujet tabou dans notre société actuelle et celle-ci s’est éloignée de notre quotidien. Cependant, celle-ci peut surgir à n’importe quel moment et de manière imprévisible.
Inversin, Philippe, Matthey, Vanina
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Balansert lederskap

open access: yesMagma, 2020
Denne artikkelen diskuterer hvordan man kan kombinere vertikalt og horisontalt lederskap effektivt i prosjekter, altså hvordan lederskapet i prosjektet kan skifte mellom teammedlemmer og den formelt utpekte prosjektlederen avhengig av situasjonens krav.
Anne Live Vaagaasar, Ralf Müller
doaj   +1 more source

Le travail prescrit à l'épreuve du réel: analyse de la mise en pratique d'un concept éducatif [PDF]

open access: yes, 2009
S’appuyant sur les apports de l’analyse de l’activité, ce travail de mémoire a pour objectif de mettre en évidence l’écart qui existe entre le travail prescrit par le concept éducatif du Foyer St-Martin « Grandir ensemble » et le travail réel effectué ...
Dekumbis, Nathalie, Levy, Bernard
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Venous wall graft in the eyelid reconstruction: observations drawn from 64 cases

open access: yesDermatology Reports, 2022
The aim of this report is to illustrate the venous wall graft and to present the observations drawn from a large series of eyelid reconstructions performed with this method.
Cesare Barbera   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Impact of Management Support on Business Intelligence Adoption: Illustrative Case Study Testing Different Managerial Strategies

open access: yesActa Informatica Pragensia
Business intelligence (BI) is a crucial tool for organizations to gain a competitive advantage on the market. BI encompasses collection, analysis and utilization of data to enhance decision-making and drive organizational innovation.
Jakub Andar, Petra Kasparova
doaj   +1 more source

Where to Initiate Basal Insulin Therapy: Inpatient or Outpatient Department? Real-World Observation in China

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2022
Minyuan Chen,1,* Puhong Zhang,1,2,* Yang Zhao,1,3 Nadila Duolikun,1 Linong Ji4 1The George Institute for Global Health, China, Beijing, 100600, People’s Republic of China; 2The George Institute for Global Health, Faculty of Medicine, University ...
Chen M   +4 more
doaj  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

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