Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal +3 more
wiley +1 more source
Continuous bidirectional coupling of heart rate variability and emotions in dyad speaker-listener dynamics reveals unique interpersonal synchronization. [PDF]
Alkhodari M +6 more
europepmc +1 more source
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
wiley +1 more source
Sympatho-vagal balance and intrinsic sinoatrial node activity in larval zebrafish quantified by heart rate variability. [PDF]
Hamed L +4 more
europepmc +1 more source
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li +7 more
wiley +1 more source
Construction of a Free-Standing Bismuth Carbon Nanofiber-Based Composite Anode Integrated with Molybdenum Disulfide for High-Performance Sodium-Ion Batteries. [PDF]
Mai G, Tian X, Mei Z, Deng Q, Yao L.
europepmc +1 more source
Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas +10 more
wiley +1 more source
Bond Softening and Elastic Confinement of Monolithic Dense Binary Alloys for High Volumetric Capacity of K-Ion Battery Anodes. [PDF]
Li Y +14 more
europepmc +1 more source
Rates of Solvolysis of Bis-p-toluenesulfoxymethylcyclohexanes [PDF]
openaire +1 more source
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng +11 more
wiley +1 more source

