Results 91 to 100 of about 1,818,251 (309)

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

AdamD: Improved bias-correction in Adam

open access: yesCoRR, 2021
Here I present a small update to the bias-correction term in the Adam optimizer that has the advantage of making smaller gradient updates in the first several steps of training. With the default bias-correction, Adam may actually make larger than requested gradient updates early in training.
openaire   +3 more sources

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Approximate Bias Correction in Econometrics [PDF]

open access: yes
This paper discusses ways to reduce the bias of consistent estimators that are biased in finite samples. It is necessary that the bias function, which relates parameter values to bias, should be estimable by computer simulation or by some other method ...
James G. MacKinnon, Anthony A. Smith Jr.
core  

Statistical Sources of Variable Selection Bias in Classification Tree Algorithms Based on the Gini Index [PDF]

open access: yes, 2005
Evidence for variable selection bias in classification tree algorithms based on the Gini Index is reviewed from the literature and embedded into a broader explanatory scheme: Variable selection bias in classification tree algorithms based on the Gini ...
Strobl, Carolin
core   +1 more source

Small sample bias correction or bias reduction?

open access: yesCommunications in Statistics - Simulation and Computation, 2019
Many problems in biomedical and other sciences are subject to biased estimates (maximum likelihood or of similar types). In two seminal papers Cox and Snell (1968) and Firth (1993) deal with first order bias of maximum likelihood estimates. Cox and Snell obtain a correction term that corrects, approximately, first order bias and Firth uses an ...
Xuemao Zhang, Sudhir Paul, You-Gan Wang
openaire   +6 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Strategic plan 2009-2010

open access: yes, 2009
Title from PDF cover (publisher's Web site, viewed Sept. 15, 2010).; "December 18, 2009"--Letter of transmittal.; Previously published: Building upon our success : strategic initiatives / State of Connecticut, Department of Correction. [Wethersfield, CT]
Connecticut. Dept. of Correction.
core  

Correction of ‘Bias factor, maximum bias and the E-value’ [PDF]

open access: yesInternational Journal of Epidemiology, 2021
Arvid Sjölander, Tyler J VanderWeele
openaire   +2 more sources

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