Results 271 to 280 of about 464,579 (330)

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Thiosulfonate‐Derived BODIPY “Stick and Glue” Strategy for Fluorescent Thiol Labeling

Angewandte Chemie, EarlyView.
We present a powerful photochemical strategy for converting disulfide bonds into stable thioether linkages via a [1,2]‐sigmatropic rearrangement. By integrating this reaction into traditional methanethiosulfonate‐based thiol labeling, we enable light‐triggered stabilization of peptide and protein conjugates with enhanced robustness and versatility ...
Lucie Šálková, David Dunlop, B. Buse Tütüncü, Zdeněk Knejzlík, Tomáš Slanina   +4 more
wiley   +2 more sources

Cultivating microbial communities from the serpentinite-hosted Prony Bay hydrothermal field on different carbon sources in hydrogen-fed bioreactors. [PDF]

Environ Microbiome
Popall RM, Roland A, Davidson S, Combet-Blanc Y, Price RE, Quéméneur M, Postec A, Erauso G.   +7 more
europepmc   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Bicarbonate-Stabilized Cu₂O/Cu Heterointerfaces Enable Efficient Ethylene Electrosynthesis From Carbon Capture Solutions. [PDF]

Small
Ma S, Hu H, Shen F, Chen Z, Hu J.
europepmc   +1 more source

Engineering Ultrasound Contrast Agents for Targeted Therapeutics: A Theranostic Approach to Drug Delivery, Gene Therapy, and Immunomodulation

Advanced NanoBiomed Research, EarlyView.
Ultrasound contrast agents, including microbubbles and nanobubbles, transform imaging and targeted therapy through precise engineering of size, shell composition, and surface properties. This review explores how these innovations enable tissue‐specific delivery, enhance therapeutic efficacy, and extend applications from vascular imaging to tumor ...
Ashkan Seza, Kimia Mozahheb Yousefi, Sara Minaeian   +2 more
wiley   +1 more source

Diphenhydramine, Sodium Bicarbonate, or Combination for Acute Peripheral Vertigo: A Randomized Clinical Trial.

JAMA Netw Open
Chi CY, Chen YC, Cheng MT, Chang KC, Chen YP, Tsai MS, Chang WT, Ma MH, Huang CH, Chiang WC.   +9 more
europepmc   +1 more source

Defects in anaplerotic metabolism sensitize <i>Staphylococcus aureus</i> small colony variants to bicarbonate. [PDF]

Microbiol Spectr
Iqbal A, Tumpa ZH, Wittliff WW, Blank BJ, Abuaita BH, Beavers WN.   +5 more
europepmc   +1 more source

Integration of metabolic parameters with SOFA score for mortality risk assessment in elderly sepsis: a derivation study. [PDF]

BMC Infect Dis
Zhu X, Li W, Lv Z, Pan X.
europepmc   +1 more source

Eine elektrokatalytische/heterogen‐katalytische Kaskade zur selektiven Herstellung von Propylenoxid durch anodische H2O2‐Erzeugung

Angewandte Chemie, EarlyView.
Diese Arbeit demonstriert eine Kaskadenstrategie für die selektive Synthese von Propylenoxid (PO) durch Kopplung der anodischen H2O2‐Erzeugung mit der TS‐1‐katalysierten Propylenepoxidierung. Durch die Immobilisierung von TS‐1 auf einer Gasdiffusionsschicht erreicht das System eine hohe PO‐Produktivität bei effizienter H2O2‐Nutzung und bietet damit ...
Shubhadeep Chandra, Anirudha Shekhawat, Adarsh Koul, Ridha Zerdoumi, Lejing Li, Wolfgang Schuhmann   +5 more
wiley   +1 more source