Results 61 to 70 of about 13,955 (172)

Co-operative Effect Between γ-Aminobutyric Acid A Receptors and Central-Type Benzodiazepine Receptors on Amylase Release in Rat Parotid Acinar Cells

Journal of Pharmacological Sciences, 2010
We investigated the inhibitory role of γ-aminobutyric acid A (GABA A ) receptors on amylase release and the evidence for functional coupling with central-type benzodiazepine receptors in rat parotid acinar cells.
Migiwa Okubo, Mitsuru Kawaguchi
doaj   +1 more source

Immature Responses to GABA in Fragile X Neurons Derived from Human Embryonic Stem Cells

Frontiers in Cellular Neuroscience, 2016
Fragile X Syndrome (FXS) is the most common form of inherited cognitive disability. However, functional deficiencies in FX neurons have been described so far almost exclusively in animal models.
Michael eTelias, Michael eTelias, Michael eTelias, Menahem eSegal, Dalit eBen-Yosef, Dalit eBen-Yosef   +5 more
doaj   +1 more source

Bicuculline, AP-7 and behavioral activity in rats

Acta Neurobiologiae Experimentalis, 1998
The effects of bicuculline (0.25 mg/kg i.p.) and AP-7 (5 nmols icv) on the processes of retrieval, consolidation of conditioned reflexes, object recognition and locomotor activity were tested in rats. Neither AP-7, nor bicuculline nor AP-7 with bicuculline changed locomotor and exploratory activity in the open field test. Co-administration of AP-7 with
Halina, Car, Magdalena, Kuziemka-Łęska, Konstanty, Wiśniewski   +2 more
openaire   +2 more sources

RETRACTED ARTICLE: Effect of apoptosis in neural stem cells treated with sevoflurane

BMC Anesthesiology, 2015
Background At present, sevoflurane inhalation anesthesia used on infants is well-known. But long-time exposure to inhalation anesthetic could cause neurologic disorder, especially nerve degeneration in infant and developing brain.
Jianlei Qiu, Pengcai Shi, Wude Mao, Yuyi Zhao, Wenshuai Liu, Yuelan Wang   +5 more
doaj   +1 more source

Intervention effect of regulating GABA-A receptor activity on the formation of experimental abdominal aortic aneurysm in rats

Scientific Reports
Abdominal aortic aneurysm is a potentially fatal vascular inflammatory disease characterized by infiltration of various inflammatory cells.The GABA-A receptor is expressed in many inflammatory cells such as macrophages and T cells and has anti ...
Jun-Xing Zhu, Can Zhou, Lu-Zhe Huang, Jian-Wei Guo, Nian-Pei Yin, Fang Yang, Yu-Da Zhang, Ying Yang   +7 more
doaj   +1 more source

EFFECT OF ELECTROACUPUNCTURE ON NOCICEPTIVE RESPONSES AFTER TOPICAL APPLICATION OF BICUCULLINE IN THE RAT

针刺研究, 1989
In this paper effect of EA on nociceptive responses after topical application of bicuculline on the cortical somatosensory area of rats was investigated.Changqiang and Yaoshu point were selected for electroacupuncture.
Xu Wei Yan Yashen Chen Zhengqiu
doaj   +2 more sources

Regulation of neutrophil migration in acute pulmonary inflammation by extraneuronal α1 gamma-aminobutyric acidA receptors

Cell Death and Disease
Acute pulmonary inflammation is a common disease on intensive care. Due to the lack of specific treatments, lethality is still very high. The ionotropic GABAA-receptors are known from the central nervous system (CNS) and have recently been detected in ...
Anika Fuhr, Robin Roediger, Mariana Simelitidis, Jutta Gamper-Tsigaras, Markus Templin, Michael Kormann, Bernd Antkowiak, Uwe Rudolph, David Köhler, Peter Rosenberger, Kristian-Christos Ngamsri, Franziska M. Konrad   +11 more
doaj   +1 more source

THE EFFECT OF GABAPENTIN ON ACETIC ACID INDUCED VISCERAL PAIN: INVOLVMENT OF MU OPIOID & GABAa RECEPTORS

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2007
BACKGROUND AND OBJECTIVES: Gabapentin is an anticonvulsant drug which also possesses antinociceptive effect in wide spectrum kind of pain, like neuropathic pain. However its effectiveness on visceral pain is not elucidated yet.
M Meimandi, GH.R Sepehri,, M Mobasher, A Parhizgar   +3 more
doaj  

The additive effect between citalopram and muscimol upon induction of antinociceptive effect in male mice

IBRO Neuroscience Reports
Previous investigations have revealed the role of GABAergic and serotonergic systems in the modulation of pain behavior. This research aimed to examine the effects of intracerebroventricular (i.c.v.) infusion of GABAA receptor agonist and antagonist as ...
Taha Shokrnejad-namin, Elnaz Amini, Fatemeh Khakpai, Mohammad-Reza Zarrindast   +3 more
doaj   +1 more source

Anxiolytic-like Effects and Increase in Locomotor Activity Induced by Infusions of NMDA into the Ventral Hippocampus in Rat: Interaction with GABAergic System

Basic and Clinical Neuroscience, 2014
Introduction: In this study, we investigated the role of N-Methyl-D-Aspartate (NMDA) receptors in the ventral hippocampus (VH) and their possible interactions with GABAA system on anxiety-like behaviors. Methods: We used an elevated-plus maze test (EPM)
Payvand Bina, Mehrnaz Rezvanfard, Shamseddin Ahmadi, Mohammad Reza Zarrindast   +3 more
doaj