Results 1 to 10 of about 3,917 (163)
Epilepsia, 2023 Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a rare inherited metabolic disorder caused by a defect of γ‐aminobutyrate (GABA) catabolism.
Itay Tokatly Latzer +15 more
semanticscholar +1 more source
γ-Aminobutyrate (GABA) Regulated Plant Defense: Mechanisms and Opportunities
Plants, 2021 Global climate change and associated adverse abiotic and biotic stress conditions affect plant growth and development, and agricultural sustainability in general.
B. Shelp +2 more
semanticscholar +1 more source
Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders
Science Advances, 2020 Major depressive disorder is linked with disturbances of gut bacterial, viral, and metabolic signatures. Gut microbiome disturbances have been implicated in major depressive disorder (MDD).
Jian Yang +30 more
semanticscholar +1 more source
Biosynthesis of 4-Aminobutyrate aminotransferase [PDF]
European Journal of Biochemistry, 1986 Mitochondrial 4-aminobutyrate aminotransferase was synthesized in a cell-free reticulocyte lysate using polysomal RNA isolated from pig brain. Its primary translation product has a higher molecular mass than the mature enzyme. The difference in relative molecular mass is approximately 2000 as revealed by SDS/polyacrylamide gel electrophoresis.
S Y, Choi, J E, Churchich
openaire +2 more sources
Impact of Plant-Based Meat Alternatives on the Gut Microbiota of Consumers: A Real-World Study
Foods, 2021 Eating less meat is increasingly seen as a healthier, more ethical option. This is leading to growing numbers of flexitarian consumers looking for plant-based meat alternatives (PBMAs) to replace at least some of the animal meat they consume.
M. Toribio-Mateas +2 more
semanticscholar +1 more source
GAB functions as a bioenergetic and signalling gatekeeper to control T cell inflammation
Nature Metabolism, 2022 γ-Aminobutyrate (GAB), the biochemical form of (GABA) γ-aminobutyric acid, participates in shaping physiological processes, including the immune response. How GAB metabolism is controlled to mediate such functions remains elusive.
Siwen Kang +9 more
semanticscholar +1 more source
Rotational dynamics of 4‐aminobutyrate aminotransferase [PDF]
FEBS Letters, 1983 The fluorescence dye 1‐anilinonaphthalene‐8‐sulfonate (ANS) was used as a probe of non‐polar binding sites in 4‐aminobutyrate aminotransferase. ANS binds to a single binding site of the dimeric protein with a K d of 6 μM. Nanosecond emission anisotropy measurements were performed on the ANS‐enzyme in an effort to detect independent rotation of the ...
Churchich, Jorge E. +2 more
openaire +2 more sources
Journal of Biological Chemistry, 2007 Protein degradation by basal constitutive autophagy is important to avoid accumulation of polyubiquitinated protein aggregates and development of neurodegenerative diseases. The polyubiquitin-binding protein p62/SQSTM1 is degraded by autophagy.
S. Pankiv +8 more
semanticscholar +1 more source
Journal of Biological Chemistry, 1979 Buthionine sulfoximine (S-n-butyl homocysteine sulfoximine), the most potent of a series of analogs of methionine sulfoximine thus far studied (Griffith, O.W., Anderson, M.E., and Meister, A. (1979) J. Biol. Chem.
O. Griffith, A. Meister
semanticscholar +1 more source
Neurochemical Research, 2013 The current knowledge of the normal biochemistry of compounds that give rise to resonances in human brain proton magnetic resonance spectra measureable at readily available field strengths (i.e. ≤3 T) is reviewed.
C. Rae
semanticscholar +1 more source