Results 11 to 20 of about 1,324 (114)

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

Journal of the Chinese Chemical Society, Volume 73, Issue 9, Page 1278-1290, September 2026.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source

Rapid Screening of Bacterial Chemoeffectors of Pseudomonas parafulva Using a CheA ATPase Activity‐Based Assay

Environmental Microbiology, Volume 28, Issue 9, September 2026.
We present a scalable, cell‐free, and straightforward NADH‐coupled CheA ATPase assay for quickly screening potential bacterial chemoeffectors and integrate it into a pipeline to identify both the chemoeffectors and their corresponding chemoreceptors in Pseudomonas parafulva, enabling systematic exploration of chemotactic sensing.
Rui Cui, Jie Li, Ni‐Ye You, Tino Krell, De‐Feng Li   +4 more
wiley   +1 more source

Evaluation of Torula Yeast (Candida utilis) Single Cell Proteins as a Partial Replacement for Soybean Meal in Broiler Diets: Effects on Productive Performance, Meat Quality Traits, and Plasma Metabolome

Journal of Animal Physiology and Animal Nutrition, Volume 110, Issue 5, Page 674-684, September 2026.
ABSTRACT Over recent years the use of yeast in feedstuffs has gained momentum due to novel developments in single‐cell proteins (SCPs). SCPs are considered a sustainable protein source, as their production enable to convert low‐value substrates (including industrial/agricultural wastes) into feed, with a related reduced environmental impact. This study
Jonathan Dayan, Marco Zampiga, Francesca Soglia, Luca Laghi, Elisa Benini, Massimiliano Petracci, Federico Sirri   +6 more
wiley   +1 more source

ω‐Hydroxyacid Dehydrogenases From Clostridium viride: Iron‐Containing Biocatalysts With Biotechnological Potential

ChemBioChem, Volume 27, Issue 16, 27 August 2026.
ω‐Hydroxy and ω‐oxo acids are precursors to lactones, polyesters, and nylon‐6, yet selective interconverting enzymes remain scarce. Clostridium viride supplies two iron alcohol dehydrogenases: Cvir‐Hbd2, restricted to C4, and the genomic singleton Cvir‐Hvd, spanning C5–C12 substrates.
Tarik Begic, Julia Hill, Jan L. Stitzel, Lukas Knauer, Volker Schünemann, Markus Räschle, Berta M. Martins, Antonio J. Pierik   +7 more
wiley   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

Epilepsia, Volume 67, Issue 8, Page 4037-4050, August 2026.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte, Afsheen Kumar, Giorgia Guerini, Massimo Pandolfo, Denise Haslinger, Colin B. Josephson, Guillermo Delgado‐García, Navprabhjot Kaur, Michaela‐Pauline Lux, Heiko Stempfle, Chantal Depondt, Reetta Kälviäinen, Felix Rosenow, Sophie von Brauchitsch, Karl Martin Klein, Andreas G. Chiocchetti   +15 more
wiley   +1 more source

Divergent Atrial Transcriptomic Signatures in Diabetic and Nondiabetic Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Diabetes alters the atrial transcriptome in atrial fibrillation, characterized by enhanced mitochondrial ATP synthesis, suppressed immune and inflammatory pathways, and distinct miRNA expression profiles, suggesting metabolic and epigenetic remodeling of the atrial substrate.
Kenshi Yoshimura, Yuya Kiriake, Hiroki Osanai, Mengyan Wei, Shinichiro Kume, Tatsuki Kurokawa, Masaki Morishima, Ryusuke Suzuki, Shinji Miyamoto, Katsushige Ono   +9 more
wiley   +1 more source

Dehydration‐driven organization of metabolites into NaDES‐like assemblies in orthodox seeds

New Phytologist, Volume 251, Issue 3, Page 1172-1187, August 2026.
Summary Desiccation tolerance in plants, especially during orthodox seed dehydration, relies on compatible solute accumulation, complex molecular mechanisms, and intermolecular organizations that remain poorly understood. We combined metabolite profiling, mass spectrometry imaging, and electrospray and cold‐spray ionization mass spectrometry to ...
Youcef Haddad, Thomas Delhaye, Emmanuelle Limanton, Denis Morineau, Maëna Le Corvec, Christine Deponge, Anne Levrel, Alain Moréac, Virginie Nazabal, David Rondeau, Ludovic Paquin, Alain Bouchereau   +11 more
wiley   +1 more source

Structure, biogenese et roles fonctionnels des poly alpha-aminobutyrates elabores sous controle bacterien dans les nodosites de Medicago sativa L

, 1985
SIGLECNRS T 57979 / INIST-CNRS - Institut de l'Information Scientifique et ...
Gerant Sauvage, D.
core  

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

Transfusion, Volume 66, Issue 7, Page 1299-1315, July 2026.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa, Sophia Delicou, Ioanna Barla, Konstantina Theocharaki, Aggeliki Kondi, Athanassios D. Velentzas, Nikolaos Simantiris, Elli‐Anna Stylianaki, George Mpekoulis, Efthymia Pavlou, Niki Vassilaki, Ioannis V. Kostopoulos, Aikaterini Xydaki, Efrosyni Nomikou, Ioanna‐Katerina Aggeli, Nikolaos Thomaidis, Evangelos Gikas, Martina Samiotaki, Jerome Zoidakis, Constantina Politis, Marianna H. Antonelou   +20 more
wiley   +1 more source

An Experimental and Educational Framework for Nonenzymatic Polyphenol Conversion: Bridging Molecular Food Science and Materials Technology through Organic Chemistry

ChemFoodChem, Volume 2, Issue 2, June 2026.
Gallic acid serves as an ideal bridge between fundamental sciences and gastronomy, as its presence as a plant polyphenol moiety. Its symmetrical, multifunctional phenolic structure makes it a perfect educational building block for linking organic chemistry both to food science and material design.
Antonio Radesco, Matteo Spagnuolo, Maria Calasso, Danilo Vona, Maria De Angelis   +4 more
wiley   +1 more source