Results 251 to 260 of about 43,019 (357)

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

The FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu, Haijiang Wang, Gunja Mishra, Lin‐Ting Wu, Chao Li, Maarten van Dinther, Jin Liu, Manuel A.F.V. Gonçalves, Peter ten Dijke, David A. Baker   +9 more
wiley   +1 more source

Predictors of Paravalvular Leakage After Transcatheter Aortic Valve Replacement in Patients With BAV: A Machine Learning Model. [PDF]

JACC Adv
Mao Y, Liu Y, Zhai M, Jin P, Chen F, Zhang G, Wei L, Liu J, Guo Y, Wu Y, Yang J.   +10 more
europepmc   +1 more source

Oral Health Status at Age 60 and 72 Years—A Longitudinal Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective This study investigated oral health status in 60‐year‐old individuals over 12 years. Materials and Methods Data were obtained from The Swedish National Study on Aging and Care (SNAC). One hundred nineteen 60‐year‐old individuals (48% females) underwent a clinical and radiographic baseline examination (2001–2003) and follow‐up ...
Sladjana Critén, Pia Andersson, Stefan Renvert, Bengt Götrick, Johan Sanmartin Berglund, Viveca Wallin Bengtsson   +5 more
wiley   +1 more source

Adult Presentation of Congenital Mitral Stenosis: The Challenges of a True Parachute Mitral Valve. [PDF]

Thorac Cardiovasc Surg Rep
Lizano MJ, Herrera Á, Induni E, Solís FE, Caldonazo T.   +4 more
europepmc   +1 more source

A Systematic Review Evaluating Methods for Diagnosis, Treatment and Prevention of Dental Erosions

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Aim The aim of this systematic review was to investigate the quality of evidence for methods used to diagnose, restore and prevent dental erosions, by evaluating and summarising clinical controlled studies and in situ studies covering this field.
Maria Skalsky Jarkander, Helena Domeij, Irene Edebert, Alfheidur Astvaldsdottir, Margaret Grindefjord, Annsofi Johannsen   +5 more
wiley   +1 more source

Temporary Mechanical Circulatory Support in the Complex Vasculopath: Redefining What Is Possible. [PDF]

JACC Case Rep
Lodewyks C, Karam J, Eckman P, Cabuay B, Newell M.   +4 more
europepmc   +1 more source

Bicuspid Aortic Valve

, 2018
Yıldırım, Ayşe Inci, Karaağaç, Aysu Türkmen   +1 more
openaire   +3 more sources

The Patient‐Centred Interdental Cleaning Concept—Consensus Based on a Round Table

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Aim To consolidate clinical and scientific evidence and develop personalised recommendations for the optimal use of interdental devices, addressing the diverse needs of patients with varying oral health conditions based on the outcomes of an expert meeting.
Tim M. J. A. Thomassen, Dagmar E. Slot, Christian Graetz, Nicola Discepoli, Johannes C. Ehrenthal, Cornelia Frese, Inmaculada Tomás, Christof E. Dörfer, Fridus (G. A.) Van der Weijden, Sonja Sälzer   +9 more
wiley   +1 more source

Clinical 4D flow MRI assessment in aortopathy-what the clinician needs to know. [PDF]

Cardiovasc Diagn Ther
Bissell MM, Garg P.
europepmc   +1 more source