Results 201 to 210 of about 111,060 (242)

A Unified Approach for the Synthesis of Conformationally Locked and sp2‐sp3 Fused Hybrids

Chemistry – A European Journal, EarlyView.
This study presents a systematic platform to build rigid sp2–sp3 hybrids via benzyne cycloadditions. Arene‑fused bicyclic oxa‐, aza‐, and carbocycles are converted into medicinally relevant amino acids and applied to Enalapril analogues synthesis. The hybrids combine aromatic interactions with 3D rigidity, tuning lipophilicity, pKa, and solubility ...
Ervis Saraci, Federica Plavi, Giovanni Viscardi, Chad N. Ungarean, Massimo Boiocchi, Christophe Salome, Quentin Lefebvre, Thomas C. Fessard, David Sarlah   +8 more
wiley   +1 more source

Electric Scooter and Electric Bicycle Injuries in Children and Adolescents: A Narrative Review of Epidemiology, Injury Patterns, Clinical Outcomes, and Prevention. [PDF]

Healthcare (Basel)
Bašković M, Lacković M, Buzuk J, Dujić B, Jurić D, Jurković K, Pehar K, Vuković S, Borić Krakar M.   +8 more
europepmc   +1 more source

Stereochemical Control in the Matteson Reaction

Chemistry – A European Journal, EarlyView.
The Matteson homologation is a highly versatile method for the stereoselective insertion of carbenoids into boronic esters. Through iterative application of the process, complex chiral molecules can be synthesized. The stereoselectivity of the reaction is determined by a chiral diol incorporated in the boronic ester.
Hae Mo Lee, Christoph Hirschhäuser
wiley   +1 more source

Divergent c-MYC Expression Patterns in NET and NEC: Insights from a Multicentre Cohort of 1380 Neuroendocrine Neoplasms. [PDF]

Endocr Pathol
Schmitt M, Ofner K, Bartsch DK, Wagner DC, Rinke A, Gress T, Kremer M, Evert M, Reitsam NG, Koberova V, Märkl B, Quaas A, Eckstein M, Steinestel K, Pagenstecher A, Keber U, Denkert C, Steiger K, Foersch S, Klöppel G, Kasajima A, Bohnenberger H, Jesinghaus M.   +22 more
europepmc   +1 more source

Cyclopropylamine‐Derived Distonic Iminium Radicals: Photoinduced Strategies in Chemo‐ and Stereo‐Selective Synthesis

Chemistry – A European Journal, EarlyView.
Cyclopropylamines have emerged as powerful photocatalytic building blocks. Upon light‐induced single‐electron oxidation, they undergo strain‐release ring opening to generate distonic iminium radicals that enable diverse transformations, including ring‐opening functionalization, formal [3 + 2] cycloadditions, radical cascades, and asymmetric bond ...
Maria Chiara Cabua, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +3 more
wiley   +1 more source

Embedded FMCW Radar Target Detection and Tracking Based on Inter-Frame Differencing and Boundary-Adaptive CA-CFAR. [PDF]

Sensors (Basel)
Zou X, Feng W, Gao B, Gao N, Chen J.
europepmc   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

An interpretable generative probabilistic framework for demand characterization and consistency checking in dock-based bicycle-sharing systems: the case of BiciMad. [PDF]

Sci Rep
Vallez CM, Contreras D, Castro M.
europepmc   +1 more source

Chiral Pyrazolinylidene Complexes for Asymmetric Catalysis

Chemistry – A European Journal, EarlyView.
The synthesis and application of pyrazolin‐5‐ylidene NHC chiral‐at‐ruthenium catalysts is reported. The strong donating pyrazolin‐5‐ylidene ligands led to highly electron rich ruthenium complexes, which showed excellent catalytic activity and enantioselectivity in the intramolecular aziridination of an alkene.
Felix Möller, Nemrud Demirel, Thomas Krüger, Linus Plohnke, Jennifer Schröder, Sergei I. Ivlev, Eric Meggers   +6 more
wiley   +1 more source

Photochemical Ring Opening of Cyclopropyl Silyl Ethers Enables β-β Coupling, Radical-Polar Crossover and Annulation. [PDF]

Angew Chem Int Ed Engl
Rydén J, Young E, Olsson W, Flodén E, Tan M, Clementson S.   +5 more
europepmc   +1 more source