Results 111 to 120 of about 29,301 (244)
Distributed Drug Discovery: Synthesis of Unnatural Amino Acids as Potential Antimalarial Drugs [PDF]
, 2015 Through the collaboration of many institutions across the globe, the Distributed Drug Discovery project founded at Indiana University-Purdue University Indianapolis seeks to aid in the development of drugs for the developing world.
Dugan, Amanda
core +1 more source
3-([4-(Acetylamino)phenyl]methoxy-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic Acid
MolbankOverexpression of protein phosphatase 5 (PP5) is linked to tumor cell growth, making it a candidate for small-molecule drug therapy. Since the PP2A domain has been selectively inhibited using functionalized scaffolds that maximize contacts, a similar ...
Kathryn N. Mayeaux +6 more
doaj +1 more source
(1S,4R)-4,7,7-Trimethyl-1-(1H-perimidin-2-yl)-2-oxabicyclo[2.2.1]heptan-3-one
MolbankPerimidine derivatives are versatile heterocycles with growing significance in medicinal chemistry and materials sciences. However, their structural variety remains limited.
Elżbieta Speina +2 more
doaj +1 more source
Six Peroxide Groups in One Molecule – Synthesis of Nine‐Membered Bicyclic Silyl Peroxides (Eur. J. Org. Chem. 31/2014) [PDF]
, 2014 Ashot V. Arzumanyan +6 more
openalex +1 more source
N\u3csup\u3e1\u3c/sup\u3e-Acetyl-3\u27-methylandrosta-4,16-dieno[16,17-\u3cem\u3ed\u3c/em\u3e]pyrazole-3-one [PDF]
, 1994 In an attempt to find the structural features promoting the thermal isomerization of the N-acylated steroid [16,17-d]pyrazoles into [17,16-c]pyrazole derivatives,the X-ray structure analysis of the title compound, C23H30N2O3, (1), has been carried out ...
Kamernitzky, Alexey V. +5 more
core +1 more source
Acta Pharmaceutica Sinica BDrug discovery is a sophisticated process that incorporates scientific innovations and cutting-edge technologies. Compared to traditional bioactivity-based screening methods, encoding and display technologies for combinatorial libraries have recently ...
Yu Fan +11 more
doaj +1 more source
Vibrational Spectra and Force Constants of Bicyclic Molecules. I. Norbornane and Norbornane-d4
Croatica Chemica Acta, 1974 Norbornan.e (bicyclo[2.2.l]heptane) and its derivatives have been extensively studied by chemical and physical methods. Since norbornane represents an important strained molecule, particular attention was payed tci its geometry1 and bonding properties2• However, no vibrational analysis of norbornane or its derivatives has been undertaiken.
Meić, Z., Randić, M., Rubčić, A.
openaire +1 more source
BioengineeringPeptide–drug conjugates (PDCs) have emerged as a next-generation therapeutic platform, combining the target specificity of peptides with the pharmacological potency of small-molecule drugs.
Krishna Jadhav +11 more
doaj +1 more source
Studies of Laurencia Natural Products and Some Synthetic Bicyclic Molecules by X-Ray Analysis [PDF]
, 1968 A. F. Cameron
openalex