Results 121 to 130 of about 29,301 (244)

An asymmetric synthesis of chiral 4,4-disubstituted cyclohexenones in high enantiomeric purity [PDF]

, 1986
Aitken, R. Alan, Lefker, Bruce A., Meyers, A. I., Wanner, Klaus Th.   +3 more
core   +1 more source

Development of scoring-assisted generative exploration (SAGE) and its application to dual inhibitor design for acetylcholinesterase and monoamine oxidase B

Journal of Cheminformatics
De novo molecular design is the process of searching chemical space for drug-like molecules with desired properties, and deep learning has been recognized as a promising solution.
Hocheol Lim
doaj   +1 more source

Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ receptor: The studies of design, synthesis, and structure–activity relationships for (4-arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivatives

, 2016
Shigeo Hayashi, Katsuyo Ohashi, Sachiko Mihara, Eriko Nakata, Chie Emoto, Atsuko Ohta   +5 more
openalex   +1 more source

Flavouring Group Evaluation 87, Revision 3 (FGE.87Rev3): Consideration of bicyclic secondary alcohols, ketones and related esters evaluated by JECFA (63rd meeting) structurally related to bicyclic secondary alcohols, ketones and related esters evaluated in FGE.47Rev1. [PDF]

EFSA J
EFSA Panel on Food Additives and Flavourings (FAF), Castle L, Andreassen M, Aquilina G, Bastos M, Boon P, Fallico B, FitzGerald R, Frutos Fernández MJ, Grasl-Kraupp B, Gundert-Remy U, Gürtler R, Houdeau E, Kurek M, Louro H, Morales P, Passamonti S, Benigni R, Degen G, Engel KH, Carfí M, Martino C.   +21 more
europepmc   +1 more source

Bridged-Bicyclic Fluorophores Push Photophysical Boundaries for Live-Cell Imaging. [PDF]

Chem Biomed Imaging
Si D, Wang L.
europepmc   +1 more source

Revealing Hidden Length by Force: Decoupling Modulus and Toughness in Network Gels. [PDF]

ACS Cent Sci
Thazhathethil S, Hu X.
europepmc   +1 more source

Discovery and chemical optimisation of a potent, Bi-cyclic antimicrobial inhibitor of Escherichia coli PBP3. [PDF]

Commun Biol
Rowland CE, Newman H, Martin TT, Dods R, Bournakas N, Wagstaff JM, Lewis N, Stanway SJ, Balmforth M, Kessler C, van Rietschoten K, Bellini D, Roper DI, Lloyd AJ, Dowson CG, Skynner MJ, Beswick P, Dawson MJ.   +17 more
europepmc   +1 more source

Total synthesis of natural products based on hydrogenation of aromatic rings. [PDF]

Beilstein J Org Chem
Wu H, Qi X.
europepmc   +1 more source

Atmospheric oxidation of dimethylsiloxanes, a source of Si=O double bonds? [PDF]

Environ Sci Pollut Res Int
Rücker C, Troegel D, Kümmerer K.
europepmc   +1 more source

High-throughput electronic property prediction of cyclic molecules with 3D-enhanced machine learning. [PDF]

Chem Sci
Zheng P, Isayev O.
europepmc   +1 more source