Results 41 to 50 of about 29,301 (244)

From 2,3-Diazabicyclo[2.2.2]oct-2-ene to Fluorazophore-L, a membrane-bound fluorescent probe for antioxidants [PDF]

, 2004
The aim of this work was to synthesize and to establish a new fluorescent membrane probe for antioxidants by exploiting the exceptional properties of the long-lived fluorophore 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) alias Fluorazophore-P.
Gramlich, Gabriela
core   +1 more source

Harnessing Photoenzymatic Systems for Intermolecular C–H Fluorination

Angewandte Chemie, EarlyView.
Despite the remarkable versatility of enzymes for catalyzing complex organic transformations under mild aqueous conditions, no biocatalytic system has been reported for intermolecular C–H fluorination. A radical photoenzymatic approach is introduced that leverages a designed de novo protein scaffold with an unnatural amino acid to achieve precise ...
Yu Zhou, Danielle Lawson, Zihan Zhang, Yunling Deng, Hejun Deng, Connor J. O'Dea, Zachariah A. Page, Yi Lu   +7 more
wiley   +2 more sources

Crystal structure of ethyl 3-amino-6-methyl-2-[(4-methylphenyl)carbamoyl]-4-[(E)-2-phenylethenyl]thieno[2,3-b]pyridine-5-carboxylate monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the title molecule, C27H25N3O3S·H2O, the dihedral angle between the planes of the thienyl ring and the pendant p-tolyl group is 39.25 (6)°, while that between the pyridine ring and the pendant phenyl ring is 44.37 (6)°.
Joel T. Mague, Mehmet Akkurt, Shaaban K. Mohamed, Etify A. Bakhite, Mustafa R. Albayati   +4 more
doaj   +1 more source

Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1 [PDF]

, 2013
Protein-based therapeutics feature large interacting surfaces. Protein folding endows structural stability to localised surface epitopes, imparting high affinity and target specificity upon interactions with binding partners.
A Patgiri, B Ibarra-Molero, BN Bullock, BR Brooks, BW Ozanne, CN Pace, D Aud, D Derossi, D Krylov, D Seebach, D Wang, D Wang, D Wang, D Wang, DA Guarracino, David P. Fairlie, DH Appella, DP Fairlie, DP Fairlie, E Vives, EF Wagner, EK O’Shea, EK O’Shea, EK O’Shea, F Bernal, F Bernal, GH Bird, GH Bird, Gloria Ruiz-Gómez, Huy N. Hoang, J Liu, JD Tyndall, JK Judice, JM Dixon, JM Mason, JM Mason, JM Mason, JM Mason, JN Glover, Jody M. Mason, Jose M. Sanchez-Ruiz, LD Walensky, LD Walensky, LK Henchey, LM Johnson, NE Shepherd, NE Shepherd, NE Shepherd, P Lavigne, PS Kutchukian, R Eferl, R Zenz, RE Moellering, RN Chapman, RO Crooks, RS Harrison, S Baek, SM Fuchs, T Wiseman, TA Libermann, Tara Rao, Timothy A. Hill, YW Kim, YW Kim   +63 more
core   +3 more sources

5-Bromo-1H-thieno[2,3-d]imidazole

Acta Crystallographica Section E, 2010
The crystal structure of the title compound, C5H3BrN2S, shows that bromination of 1H-thieno[2,3-d]imidazole with N-bromosuccinimide in acetonitrile occurs at position 5 of the bicyclic system. The molecule is almost planar, with a mean deviation of 0.015&
Fen Wang, Sacha Ninkovic, Michael Collins, Curtis Moore, Arnold L. Rheingold, Alex Yanovsky   +5 more
doaj   +1 more source

Building on Cram's legacy: stimulated gating in hemicarcerands. [PDF]

, 2014
CONSPECTUS: Donald Cram's pioneering Nobel Prize-winning work on host-guest molecules led eventually to his creation of the field of container molecules. Cram defined two types of container molecules: carcerands and hemicarcerands.
Helgeson, Roger C, Houk, KN, Liu, Fang
core   +2 more sources

1,1′-[(1E,11E)-5,8-Dioxa-2,11-diazoniadodeca-1,11-diene-1,12-diyl]dinaphthalen-2-olate

Acta Crystallographica Section E, 2011
The title compound, C28H28N2O4, crystallizes in a zwitterionic form with deprotonated naphthol hydroxy groups and protonated imine N atoms. The asymmetric unit contains one half-molecule located on a twofold rotation axis.
Yanju Liu, Kai Liu, Zhiqiang Cao, Meiju Niu   +3 more
doaj   +1 more source

Development of peptidomimetic ligands of Pro-Leu-Gly-NH2 as allosteric modulators of the dopamine D2 receptor

Beilstein Journal of Organic Chemistry, 2013
A variety of stable, small-molecule peptidomimetic ligands have been developed to elucidate the mechanism by which the neuropeptide Pro-Leu-Gly-NH2 (PLG) modulates dopaminergic neurotransmission.
Swapna Bhagwanth, Ram K. Mishra, Rodney L. Johnson   +2 more
doaj   +1 more source

NORBORNADIENO: SÍNTESE E APLICAÇÕES

Química Nova, 2022
Bicyclo[2.2.1]hepta-2,5-diene or norbornadiene (NBD) is a bicyclic hydrocarbon molecule used in many fields of chemistry since its first synthesis in 1950. NBD is the precursor of Aldrin, an agrochemical that was commonly used as an insecticide until the
Anni C. S. Gomes, Antonio J. Demuner, Bryan N. S. Pinto, Elson S. Alvarenga   +3 more
doaj   +1 more source

Betalains in some species of the amaranthaceae family: A review [PDF]

, 2018
Natural pigments are largely distributed in the plant kingdom. They belong to diverse groups, with distinct biochemical pathways. Betalains with colours that range from yellow to red-violet can de divided into two main subgroups: betaxanthins and ...
Ali, Barua, Bhujbal, Bucur, Bussmann, Böhm, Clemente, Corio-Costet, Dinda, Guo, Križnic, Kumar, Liu, Malomo, Mujica, Mulinacci, Narayanan, Nidavani, Pavoković, Pietrzkowski, Popa, Ramachandran, Rehman, Rub, Salvador, Saqib, Saritha, Shao, Surse, Telagari, Vendruscolo, Yaacob   +31 more
core   +2 more sources