Results 71 to 80 of about 464,601 (309)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Investigation of simultaneous 2R regeneration of two 40 Gb/s channels in a single optical fiber [PDF]

, 2008
We experimentally investigate the simultaneous all-optical signal processing of two 40-Gb/s wavelength-division multiplexing optical streams spaced by ~5 nm using self-phase modulation and offset filtering in a single highly nonlinear fiber to achieve a ...
Provost, L., Parmigiani, F., Petropoulos, P., Richardson, D.J.   +3 more
core   +1 more source

Obesity and cancer: unravelling the microbiome’s hidden role

Frontiers in Nutrition
Obesity has been implicated as the driving force of many diseases including cancer through multiple biological mechanisms, including gut microbial imbalances, compromised intestinal barrier integrity, persistent low-grade inflammation, and alterations in
Christine Gaskell, Ross MacDonald, Eiman Aleem, Ghizlane Bendriss   +3 more
doaj   +1 more source

Rhytidectomy Utilizing Bidirectional Self-Retaining Sutures: The Bidirectional Lift and the Extended Bidirectional Lift [PDF]

Aesthetic Surgery Journal, 2015
This article outlines a new rhytidectomy technique, developed by the author, that utilizes bidirectional self-retaining (barbed) sutures for superficial musculoaponeurotic system (SMAS) plication and, in some instances, skin closures. Short-scar and traditional versions of the procedure are presented, and the history of purse-string SMAS plication and ...
openaire   +2 more sources

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Global Ionosphere Total Electron Content Prediction Based on Bidirectional Denoising Wavelet Transform Convolution

Atmosphere
The Denoising Wavelet Transform Convolutional Long Short-Term Memory Network (DWTConvLSTM) is a novel ionospheric total electron content (TEC) spatiotemporal prediction model proposed in 2025 that can simultaneously consider high-frequency and low ...
Liwei Sun, Guoming Yuan, Huijun Le, Xingyue Yao, Shijia Li, Haijun Liu   +5 more
doaj   +1 more source

Associations Between Biomarkers of Alzheimer's Disease and Sleep in Cognitively Unimpaired Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter, Hans Dorn, Julian Hellmann‐Regen, Ana Bueno‐Lopez, Verena van Ginneken, Heidi Danker‐Hopfe   +5 more
wiley   +1 more source

Semantic Bidirectionalization Revisited [PDF]

, 2014
A bidirectional transformation is a pair of mappings between source and view data objects, one in each direction. When the view is modified, the source is updated accordingly with respect to some laws.
Shayan Najd, Wang, Meng,, Najd Javadipour, Shayan,, Najd, Shayan, Meng Wang, Wang, Meng, Najd Javadipour, Shayan   +6 more
core   +1 more source

Disentangling the Genetic Relationship Between Sleep and Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A bidirectional relationship between sleep and epilepsy is well recognised, yet the biological mechanisms linking them remain poorly understood. Both have a genetic basis, with genome‐wide association studies (GWAS) capturing polygenic contributions.
Khang N. Le, Victoria E. Jackson, Rachel E. Stirling, Zachary F. Gerring, Remi Stevelink, Samuel F. Berkovic, Ingrid E. Scheffer, Philippa J. Karoly, Melanie Bahlo, Karen L. Oliver   +9 more
wiley   +1 more source

Bidirectional A*: comparing balanced and symmetric heuristic methods [PDF]

A widely known algorithm for ¯nding the shortest path in a network is Bidirectional A*. The version of bidirectional A* that is considered the most appropriatehitherto, uses so-called balanced heuristic estimates.
Post, H., Pijls, W.H.L.M.
core