Results 141 to 150 of about 147,894 (384)

A Frank Assessment of SHANK: Impacts of Pathogenic Variations in SHANK3 on Preclinical Models of Phelan McDermid Syndrome

Autism Research, EarlyView.
ABSTRACT Although there are as many as 40 preclinical models of the neurodevelopmental disorder Phelan McDermid syndrome (PMS, or 22q13.3 deletion syndrome), detailed phenotypic analyses to compare the effects of different pathogenic variants and inform treatment design are lacking.
Vic Lin, Samantha M. Matta, Julia E. Dallman, Suzanne Hosie, Manon Moreau, Ashley E. Franks, Thomas Bourgeron, Elisa L. Hill‐Yardin   +7 more
wiley   +1 more source

2’-Fucosyllactose modulates the function of intestinal microbiota to reduce intestinal permeability in mice colonized by feces from healthy infants

Food Science and Human Wellness
2’-Fucosyllactose (2’-FL) shows the potential to support intestinal health as a natural prebiotic that bridges the gap between infant formula feeding and breastfeeding.
Qingxue Chen, Liu Yang, Fangqin Xiang, Ignatius Man-Yau Szeto, Yalu Yan, Biao Liu, Jinju Cheng, Lu Liu, Bailiang Li, Sufang Duan   +9 more
doaj   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

Effects of a Multi-Strain Supplement Combination Lactobacillus and Bifidobacterium on Anthropometric Measurements and Body Fat Percentage in Adults with Overweight and Obesity [PDF]

Iranian Journal of Diabetes and Obesity
Objective: Probiotics are living microorganisms that play a part in energy balance. One of the most important causes of obesity is dysbiosis in the intestinal microbiota composition.
Maryam Izanlou, Abolghassem Djazayery, Seyed Ali Keshavarz   +2 more
doaj  

POSSIBLE ROLE OF PROBIOTIC MICROORGANISMS OF BIFIDOBACTERIUM AND LACTOBACILLUS GENUS IN PATHOGENESIS OF AUTOIMMUNE THYROID DISEASES

Медицинская иммунология, 2014
It was revealed, that, in blood samples of the patients with autoimmune thyroid diseases, serum antibodies against cell-free fraction of Bifidobacterium bifidum 791 and Lactobacillus plantarum B-01 were detected, respectively, in 71 and 63% of cases ...
E. P. Kiseleva, O. V. Tsyganova, K. I. Mikhailopulo, O. V. Sviridov, Y. E. Demidchic, A. V. Izhik, Y. A. Knirel, G. I. Novik   +7 more
doaj   +1 more source

Antagonistic Effect of Intestinal Bacteria from the Microflora of Holoxenic (Conventional) Piglets, Against Clostridium Perfringens in the Digestive Tract of Gnotoxenic Mice and Gnotoxenic Piglets [PDF]

, 1978
Antagonistic effect of piglet microflora against Clostridium perfringens was studied in germfree mice, to isolate bacterial strains responsible for this colonization resistance.
Corpet, Denis E., Nicolas, Jean-Louis
core   +1 more source

Tolerance and safety of the potentially probiotic strain Lactobacillus rhamnosus PRSF-L477 : a randomised, double-blind placebo-controlled trial in healthy volunteers [PDF]

, 2010
In Europe, the species Lactobacillus rhamnosus is currently on the Qualified Presumption of Safety list used by the European Food Safety Authority (EFSA) for internal safety assessment, but according to the EFSA the species should remain a topic of ...
Huys, Geert, Klare, Ingo, Knol, Jan, Tolboom, Hermien, Wind, Richèle D   +4 more
core   +3 more sources

Bifidobacterium Abundance in Early Infancy and Vaccine Response at 2 Years of Age

Pediatrics, 2019
By following a birth cohort through 2 years of age, Bifidobacterium abundance in early infancy was seen to predict better vaccine responses later in life. BACKGROUND: The intestinal microbiome in early infancy affects immunologic development and thus may
M. N. Huda, Shaikh M. Ahmad, M. J. Alam, Afsana Khanam, K. Kalanetra, Diana H. Taft, R. Raqib, M. Underwood, David A. Mills, Charles B. Stephensen   +9 more
semanticscholar   +1 more source

Antibiotic Susceptibility of Bifidobacterium thermophilum and Bifidobacterium pseudolongum Isolates from Animal Sources

Journal of Food Protection, 2007
The widespread use of antimicrobial substances has led to resistant populations of microorganisms in several ecosystems. In animal husbandry, the application of antibiotics has contributed to resistance development in pathogenic and commensal bacteria. These strains or their resistance genes can be spread along several ecological routes, including the ...
Mayrhofer, S., Konrad, J.D., Amtmann, E., van Hoek, A.H.A.M., Petersson, A., Mair, C., Mayer, H.K., Kneifel, W.   +7 more
openaire   +4 more sources

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source