Results 241 to 250 of about 147,894 (384)

Gut Microbiota Regulate Lipid Metabolism via the Bile Acid Pathway: Resistance to Hypoxia in Gansu Zokor (Eospalax cansus)

open access: yesIntegrative Zoology, EarlyView.
The gut microbiota regulates lipid metabolism of Gansu zokor (Eospalax cansus) through the bile acid pathway in hypoxic environments, reflecting the unique survival strategy of subterranean rodents to maintain lipid metabolism homeostasis and flexible energy metabolism in hypoxic environments.
Maohong Yang   +5 more
wiley   +1 more source

L‐Tryptophan Produced by Bifidobacterium pseudocatenulatum NCU‐08 Delays Aging in SAMP8 Mice by Activating the Sirt1/P53/P21/Rb Signaling Pathway

open access: yesAging Cell, EarlyView.
Bifidobacterium pseudocatenulatum NCU‐08, isolated from the feces of centenarians, facilitated the entry of L‐tryptophan into hippocampal neurons of SAMP8 mice, where it was metabolized into NAD+. The increased NAD+ levels activated Sirt1 protein, thereby suppressing the expression of senescence‐associated proteins P53, P21, and Rb, ultimately delaying
Tangchang Xu   +8 more
wiley   +1 more source

Bifidobacterium boosts anti-PD-1 effectiveness through JAK pathway in hepatocellular carcinoma. [PDF]

open access: yesNPJ Precis Oncol
Huo R   +21 more
europepmc   +1 more source

Sex‐Specific Aging Patterns of Gut Microbiota in Urban Chinese Adults: Guild‐Based Analysis and Implications for Healthy Aging

open access: yesAging Cell, EarlyView.
This study employed a guild‐based approach to identify sex‐specific age‐related gut microbiota in two large cohorts of Chinese adults. The microbial age, derived from the significant guilds identified, was higher in women and less healthy individuals, was associated with an increased risk of type 2 diabetes, and could be slowed by healthy lifestyles ...
Jiongxing Fu   +8 more
wiley   +1 more source

The effect of alcohol withdrawal therapy on gut microbiota in alcohol use disorder and its link to inflammation and craving

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
This study investigates the effect of alcohol withdrawal therapy on the gut microbiome and its relationship to specific interleukins and alcohol craving. Alcohol withdrawal affected microbiome composition and increased the concentration of the butyrate pathway, along with the overall bacterial load.
Phileas J. Proskynitopoulos   +11 more
wiley   +1 more source

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