Results 141 to 150 of about 24,236,404 (304)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Big Data Analytics: principles, trends and tasks (a survey)
, 2019 We review directions (avenues) of Big Data analysis and their practical meaning as well as problems and tasks in this field. Big Data Analytics appears a dominant trend in development of modern information technologies for management and planning in ...
Balabanov, O.S.
core
, 2016 The value that can be extracted from big data greatly motivates organizations to explore data analytics technologies for better decision making and problem solving in a wide range of application domains.
Yali Zhao +7 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
A Multimodal Recommender System Using Deep Learning Techniques Combining Review Texts and Images
Applied SciencesOnline reviews that consist of texts and images are an essential source of information for alleviating data sparsity in recommender system studies.
Euiju Jeong +5 more
doaj +1 more source
Understanding the University Student Experience Through Big Data Analytics
Despite best efforts, the student experience remains poorly understood. One under-explored approach to understanding the student experience is the use of big data analytics.
Torrisi-Steele, Geraldine +2 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Distributed Analytics For Big Data: A Survey
NeurocomputingIn recent years, a constant and fast information growing has characterized digital applications in the majority of real-life scenarios. Thus, a new information asset, namely Big Data, has been defined and lead to different challenges, mainly related to data storage, management and analysis.
Berloco, Francesco +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source