Results 121 to 130 of about 24,236,404 (304)
BMC Bioinformatics, 2019 Background The Bacteria Biotope (BB) task is a biomedical relation extraction (RE) that aims to study the interaction between bacteria and their locations. This task is considered to pertain to fundamental knowledge in applied microbiology. Some previous
Amarin Jettakul +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Big data in healthcare has improved the care quality! A reality or myth?
Health is wealth, this old-age adage is a universal truth and the desire to remain healthy is the need of mankind. Healthcare is a priority for people, and technology helps to improve care quality and health management.
Yong, J. +7 more
core +1 more source
Implementing a framework for big data anonymity and analytics access control
, 2017 Analytics in big data is maturing and moving towards mass adoption. The emergence of analytics increases the need for innovative tools and methodologies to protect data against privacy violation.
Shahrestani, Seyed A. (R10567) +2 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Perspectives on Big Data and Big Data Analytics [PDF]
Database Systems Journal, 2012 Nowadays companies are starting to realize the importance of using more data in order to support decision for their strategies. It was said and proved through study cases that “More data usually beats better algorithms”. With this statement companies started to realize that they can chose to invest more in processing larger sets of data rather than ...
Elena Geanina ULARU +3 more
openaire +1 more source
Southern Company Generation Data Analytics Overview
, 2016 Presented on September 6, 2016 from 9:15 a.m.-10:00 a.m. at the Klaus Advanced Computing Building, Room 1116W, Georgia Institute of Technology.South Big Data Innovation Hub ; Applications of Analytics and Machine Learning in Energy Industry-Academia ...
Patanian, John, Jones, Randy
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source