Results 91 to 100 of about 115,029 (313)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Big Data Coordination Platform Budget and Budget Narrative
, 2016 Big Data Coordination Platform Budget and Budget ...
CGIAR Platform for Big Data in Agriculture
core
Timor-Leste enables data-driven fisheries management with adoption and integration of PeskAAS [PDF]
, 2022 The PeskAAS system was adopted and paid for by the Government of Timor-Leste (GOTL) as part of the annual budget. In providing catch and effort information for the national fishing fleet, it is now the platform for data-driven fisheries decision-making ...
CGIAR Platform for Big Data in Agriculture
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Ontology-Based Generation of Data Platform Assets
, 2023 The design and management of modern big data platforms are extremely complex. It requires carefully integrating multiple storage and computational platforms as well as implementing approaches to protect and audit data access.
Fenu G. +8 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Global Agricultural Data Innovation and Acceleration Network (GARDIAN) [PDF]
, 2022 GARDIAN already showcases CGIAR research for researchers, funders, and other stakeholders, helping advance CGIAR's public goods mandate and enhancing the potential for innovation and impact.
CGIAR Platform for Big Data in Agriculture
core
A Big Data Application in Manufacturing Industry-Computer Vision To Detect Defects on Bearings
, 2022 Ankura;et al.;Hitachi;KPMG Consulting Co., Ltd.;NTT Data Intellilink Corporation;Think in Data Initiative, Association Inc2022 IEEE International Conference on Big Data, Big Data 2022 -- 17 December 2022 through 20 December 2022 -- 186390In the ...
Koçal, C.I. +6 more
core +1 more source
The Hiperwall Visualization Platform for Big Data Research
CoRR, 2018 16 pages, 6 figures, 1 ...
Muhammad Saleem +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source