Results 71 to 80 of about 115,029 (313)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Target Population of Environment (TPE) modelling as a synergy between Big Data Platform (BDP) and Excellence in Breeding (EiB) platforms [PDF]

open access: yes, 2022
A tool has been developed that offers a crop modeling framework that provides support for environment classification (TPE) and crop trait analysis.
CGIAR Platform for Big Data in Agriculture
core  

Evolutionary trends of respiratory syncytial viruses: Insights from large-scale surveillance and molecular dynamics of G glycoprotein

open access: yesHeliyon
Human respiratory syncytial virus (RSV) is an underlying cause of lower respiratory illnesses in children, elderly and immunocompromised adults. RSV contains multiple structural and non-structural proteins with two major glycoproteins that control the ...
Muhammad Nabeel Amjad   +11 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

BIG DATA Ontologies Community of Practice – Work Plan 2017

open access: yes, 2019
Given the multi-disciplinary nature of the CGIAR Big Data For Agriculture, the Ontologyies Community of Practice (CoP) will span the knowledge domains of importance for the platform with the objective of establishing best practices, guidelines in the ...
CGIAR Platform for Big Data in Agriculture
core  

Efficient WO3 Nanoplate Arrays Photoanode Modified by ZnO Nanosheets for Enhanced Charge Separation and Transfer to Promote Photoelectrochemical Performances

open access: yesAdvanced Electronic Materials
A key factor in the photoelectrochemical (PEC) performance of photoelectrodes is the efficient separation and transfer of photogenerated charges. Herein, a novel photoanode comprising three‐dimensional (3D) WO3 nanoplate@ZnO nanosheet hierarchical type ...
Weihao Wu   +6 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

CGIAR Platform for Big Data in Agriculture - Plan of Work and Budget 2018

open access: yes, 2018
This Plan of Work and Budget (POWB) for 2018 includes chapters on the following: 1) expected key results, 2) planning for platform effectiveness and efficiency, and 3) platform management. There are also a number of tables at the end, relating to planned
CGIAR Platform for Big Data in Agriculture
core  

Project “Text Mining & Analytics Platform” [TERIN-ICT-HPC] – Project “Gate-hum (Grid Access to e-humanities)” - [TERIN-ICT-HPC] Reference: ICT-PD59-001_report_BIGdataTechnopole_dic2021

open access: yes, 2021
Project “Text Mining & Analytics Platform” [TERIN-ICT-HPC] Project Gate-hum (Grid access to e-humanities)- Big data in digital humanities & heritage platform gate-hum - [TERIN-ICT-HPC] - Text Mining in Multilingual Textual Corpora; Web Crawling ...
Migliori S., Alderuccio D.
core  

Efficient Computation of the Well-Founded Semantics over Big Data [PDF]

open access: yes, 2014
Data originating from theWeb, sensor readings and social media result in increasingly huge datasets. The so called Big Data comes with new scientific and technological challenges while creating new opportunities, hence the increasing interest in academia
Faber, Wolfgang   +2 more
core   +1 more source

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