Results 101 to 110 of about 8,175,112 (344)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Relationship between Personality Traits and Counterproductive Work Behaviors

open access: yesPsico-USF, 2016
Following the growing interest in identifying whether personality traits are associated with employee's inclination toward counterproductive work behavior (CWB), the objective of this study was to investigate the relationship between personality traits ...
Mônica Freitas Ferreira   +1 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Kepribadian Big Five dan Kepemimpinan: Tinjauan Literatur

open access: yesJurnal Penelitian Pendidikan, Psikologi dan Kesehatan
Keterbukaan (openness), kehati-hatian (conscientiousness), ekstraversi (extraversion), keramahan (agreeableness) dan neurotic (neuroticism), atau yang biasa dikenal sebagai kepribadian big five diketahui dapat memprediksi kepemimpinan. Tinjauan literatur
Lukman Layli
doaj   +1 more source

On the Quantum Resolution of Cosmological Singularities using AdS/CFT

open access: yes, 2012
The AdS/CFT correspondence allows us to map a dynamical cosmology to a dual quantum field theory living on the boundary of spacetime. Specifically, we study a five-dimensional model cosmology in type IIB supergravity, where the dual theory is an unstable
Craps, Ben, Hertog, Thomas, Turok, Neil
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

On the Galactic Evolution of $D$ and $^3He$

open access: yes, 1993
The determined abundances of primordial $^4He$ and $^7Li$ provide a basis with which to test the standard model of big bang nucleosynthesis in conjunction with the other two light element isotopes $D$ and $^3He$, also produced in the big bang.
Olive, Keith A.   +2 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Alexithymia measured with the TAS-20 questionnaire: Determining the validity of the factor structure and its relation to life satisfaction and the Big Five personality traits [PDF]

open access: yesPsihološka Istraživanja, 2018
Alexithymia is the inability of an individual to recognize their own or someone else's feelings and to communicate their own emotional states. On the cognitive level, we can observe a decreased ability for imagination and a practical style of thinking ...
Rokvić Nikola, Jovanović Tamara
doaj  

Selected personality data from the SAPA-Project: On the structure of phrased self-report items

open access: yesJournal of Open Psychology Data, 2015
These data were collected to evaluate the structure of personality constructs in the temperament domain. In the context of modern personality theory, these constructs are typically construed in terms of the Big Five (Conscientiousness, Agreeableness ...
David M Condon, William Revelle
doaj   +1 more source

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