Results 51 to 60 of about 2,341,004 (290)

Mega-History and the 21st century singularity puzzle [PDF]

Философия и космология, 2015
A series of calculations carried out independently by the Australian, Russian and American re- searchers have demonstrated that a crucial global polyfurcation is expected near the middle of the 21st century. This result is drawn by extrapolating into the
Akop P. Nazaretyan
doaj  

Rocketing to Energy Sustainability

Journal of Big History, 2018
Metaphors are an important way to facilitate understanding of new processes. This metaphor is constructed based similarity of a rocket’s and civilization’s transition from one stable state to another at a higher level accomplished using a limited supply
David LePoire
doaj   +1 more source

A History of Cosmic Habitability

Journal of Big History, 2020
Our understanding of the universe is based on the big bang cosmological model, which describes an expanding universe whose development began 13.8 billion years ago from a hot, dense state.
Amedeo Balbi
doaj   +1 more source

From Cosmos to Intelligent Life: The Four Ages of Astrobiology

, 2012
The history of life on Earth and in other potential life-bearing planetary platforms is deeply linked to the history of the universe. Since life as we know it relies on chemical elements forged in dying heavy stars, the universe needs to be old enough ...
Abel, Arrhenius, Bonner, Fenchel, Fitz, Gleiser, Kaltenegger, Lunine, Marcelo Gleiser, Oparin, Prigogine, Salama, Smoot, Susskind, Susskind, Ward, Webb, Weinberg   +17 more
core   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Chemical Evolution in Big History

ГЛОБАЛИСТИКА-2023, 2023
Unfortunately, there is insufficient research on the course of chemical evolution within the framework of the study of both Big History and evolution. The lack of attention to chemical evolution is all the more disappointing since it is a very important part of megaevolution and Big History, which at some of its stages even act as the leading line (in ...
openaire   +1 more source

Dark Before Light: Testing the Cosmic Expansion History through the Cosmic Microwave Background

, 2010
The cosmic expansion history proceeds in broad terms from a radiation dominated epoch to matter domination to an accelerated, dark energy dominated epoch.
, A. Lewis, Eric V Linder, G. Barenboim, M. Lueker ., N. Jarosik ., S. Das ., Tristan L Smith, W. Hu   +8 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Evolução do Sistema Solar Primordial em Termos de Grande História e Evolução Universal

Journal of Big History, 2018
A presente contribuição é dedicada a alguns aspectos da história e evolução do Sistema Solar primordial. A origem do Sol, da Terra, de outros planetas e dos seus satélites tem sido de grande interesse para as pessoas.
Leonid Grinin
doaj   +1 more source