Results 51 to 60 of about 165,904 (262)

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

“The keen longing for unified, all-embracing knowledge” Big History, Cosmic Evolution, and New Research Agendas

open access: yesJournal of Big History, 2019
This article offers an interpretation of recent attempts at the unification of knowledge. It argues that today’s scholarly world is aberrant. It is splintered into distinct scholarly disciplines to such an extent that universities and research ...
David Christian
doaj   +1 more source

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita   +5 more
wiley   +1 more source

Introduction. From the History of Humankind to Big History

open access: yes, 2019
Our Yearbook ‘History and Mathematics’ has already celebrated its 10th anniversary and has confidently entered its second decade. In this regard it will be quite reasonable to try to extend the scope of its research field. Therefore, this issue is designed in an unusual manner while still preserving the relevance for our approach (see about it below ...
Grinin, Leonid, Korotayev, Andrey
openaire   +2 more sources

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte   +5 more
wiley   +1 more source

Bioethics as a transdisciplinary science of complexity: A co-evolutionary introduction since the big history

open access: yesRevista Colombiana de Bioética, 2016
The main objective of this work is to expand the bioethics notion expressed in the Article 17th of the Universal Declaration on Bioethics and Human Rights, concerning the interconnections between human beings and other life forms.
Javier Collado Ruano
doaj   +1 more source

Psychosocial Functioning After Pediatric Bone Sarcoma: Generic and Survivor‐Specific Outcomes in Adolescent and Young Adult Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek   +14 more
wiley   +1 more source

Beachcombing and Coastal Settlement: The Long Migration from South Africa to Patagonia— The Greatest Journey Ever Made

open access: yesJournal of Big History, 2019
Although studies of prehistoric human migration now run into the hundreds, a single, chronological narrative of the peopling of the planet has not yet been presented, Most studies have been produced by specialists of a region.
Barry Wood
doaj   +1 more source

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos   +2 more
wiley   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla   +6 more
wiley   +1 more source

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