Results 61 to 70 of about 2,341,004 (290)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

The 21st Century Singularity and its Big History Implications: A re-analysis

open access: yesJournal of Big History, 2018
The idea that in the near future we should expect “the Singularity” has become quite popular recently, primarily thanks to the activities of Google technical director in the field of machine training Raymond Kurzweil and his book The Singularity Is Near (
Andrey Korotayev
doaj   +1 more source

Inflationary and Deflationary Branches in Extended Pre--Big Bang Cosmology

open access: yes, 1996
The pre--big bang cosmological scenario is studied within the context of the Brans--Dicke theory of gravity. An epoch of superinflationary expansion may occur in the pre--big bang phase of the Universe's history in a certain region of parameter space ...
A. A. Kehagias   +74 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Towards a Big History Model for Italian Schools: The Convergence of Knowledge from Many Disciplines

open access: yesJournal of Big History, 2019
To quote the psychologist Jerome Bruner, “Schooling is only one small part of how culture inducts the young into its canonical ways.” This “small part” has become much smaller in recent decades.
Adalberto Codetta Raiteri   +3 more
doaj   +1 more source

On Gauge Invariant Cosmological Perturbations in UV-modified Horava Gravity: A Brief Introduction [PDF]

open access: yes, 2017
We revisit gauge invariant cosmological perturbations in UV-modified, z = 3 Horava gravity with one scalar matter field, which has been proposed as a renormalizable gravity theory without the ghost problem in four dimensions.
Park, Mu-In
core   +3 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

“The keen longing for unified, all-embracing knowledge” Big History, Cosmic Evolution, and New Research Agendas

open access: yesJournal of Big History, 2019
This article offers an interpretation of recent attempts at the unification of knowledge. It argues that today’s scholarly world is aberrant. It is splintered into distinct scholarly disciplines to such an extent that universities and research ...
David Christian
doaj   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy