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Safety Assessment of Polyaminopropyl Biguanide (Polyhexamethylene Biguanide Hydrochloride) as Used in Cosmetics

International Journal of Toxicology, 2020
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of Polyaminopropyl Biguanide (polyhexamethylene biguanide hydrochloride), which functions as a preservative in cosmetic products. The Panel reviewed relevant data relating to the safety of this ingredient and concluded that Polyaminopropyl Biguanide is safe in cosmetics in the
Ronald C. Shank   +12 more
openaire   +4 more sources

Review of Biguanide (Metformin) Toxicity

Journal of Intensive Care Medicine, 2018
In the 1920s, guanidine, the active component of Galega officinalis, was shown to lower glucose levels and used to synthesize several antidiabetic compounds. Metformin (1,1 dimethylbiguanide) is the most well-known and currently the only marketed biguanide in the United States, United Kingdom, Canada, and Australia for the treatment of non-insulin ...
Christopher Hoyte   +3 more
openaire   +4 more sources

Simultaneous Interfacial Modification and Crystallization Control by Biguanide Hydrochloride for Stable Perovskite Solar Cells with PCE of 24.4%

Advances in Materials, 2021
Interfacial modification, which serves multiple roles, is vital for the fabrication of efficient and stable perovskite solar cells. Here, a multifunctional interfacial material, biguanide hydrochloride (BGCl), is introduced between tin oxide (SnO2) and ...
Zhuang Xiong   +14 more
semanticscholar   +1 more source

Poly(hexamethylene biguanide) hydrochloride (PHMB)-based materials: synthesis, modification, properties, determination, and application

Polymer Chemistry, 2023
As one of the major derivatives of biguanides, poly(hexamethylene biguanide) hydrochloride (PHMB) is a well-known commercially available polycationic antiseptic and disinfectant.
Wenyi Wang   +4 more
semanticscholar   +1 more source

Polyhexamethylene biguanide hydrochloride (PHMB)-properties and application of an antiseptic agent. A narrative review

European Journal of Ophthalmology, 2022
The prevention and management of ocular surface infections is still one of the great challenges for ophthalmologists. The spread of antimicrobial resistance makes it necessary to use antiseptic substances with a broad antimicrobial spectrum ...
Alfredo Niro   +13 more
semanticscholar   +1 more source

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