Results 131 to 140 of about 963 (180)

Bilastine in allergic rhinoconjunctivitis and urticaria

open access: yesAllergy: European Journal of Allergy and Clinical Immunology, 2010
To cite this article: Bachert C, Kuna P, Zuberbier T. Bilastine in allergic rhinoconjunctivitis and urticaria. Allergy 2010; 65 (Suppl. 93): 1–13.AbstractAllergic rhinoconjunctivitis and urticaria are increasing in prevalence in many developed countries.
Torsten Zuberbier   +2 more
exaly   +3 more sources

Bilastine: an environmental risk assessment

open access: yesDrug and Chemical Toxicology, 2015
Bilastine is a new oral selective, non-sedating histamine H1 antagonist for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria. The European Medicines Agency requires an Environmental Risk Assessment (ERA) for all novel medicines for human use.To calculate the bilastine predicted environmental concentration in surface water (PECsw;
María Luisa, Lucero   +2 more
openaire   +3 more sources

An overview of bilastine metabolism during preclinical investigations

Drug and Chemical Toxicology, 2012
Knowledge of the biotransformation of oral H₁ antihistamines is clinically important because it can define their pharmacokinetic profile through possible effects on absorption (i.e., first-pass metabolism) and elimination. Further, clinically significant interactions with inhibitors of cytochrome P450 (CYP) have previously been reported for drugs of ...
Mónica Betanzos
exaly   +3 more sources

Comparison of the efficacy and safety of bilastine 20 mg vs desloratadine 5 mg in seasonal allergic rhinitis patients

open access: yesAllergy: European Journal of Allergy and Clinical Immunology, 2009
Bilastine is a novel, nonsedating H-1-antihistamine developed for symptomatic treatment of Allergic Rhinitis and Chronic Idiopathic Urticaria. The objective of this study was to compare the efficacy and safety of bilastine 20 mg vs placebo and ...
Paul van de Heyning   +2 more
exaly   +2 more sources

Bilastine for the treatment of urticaria

Expert Opinion on Pharmacotherapy, 2013
Urticaria is a highly prevalent disease among people. First-choice treatment continues to be centred on the second-generation H1 antihistamines, including a wide group of drugs with a better therapeutic index (or risk:benefit ratio) than the classic ones, even in the high, off-label dosage occasionally required in chronic urticaria.
Ignacio, Jáuregui   +8 more
openaire   +4 more sources

Ocular Biodistribution of Once-Daily 0.6% Bilastine Eye Drops Reveals Highest Levels in Conjunctiva Up to 24 h Postadministration

open access: yesJournal of Ocular Pharmacology and Therapeutics, 2022
PURPOSE: Bilastine is a second-generation antihistamine that has been shown to be effective for treatment of allergic conjunctivitis. The objective of this study was to evaluate the pharmacokinetics (PKs) and biodistribution of 0.6% bilastine ...
Gonzalo, Ana   +4 more
exaly   +2 more sources

Bilastine for the relief of allergy symptoms

Drugs of Today, 2011
Bilastine is a potent inhibitor of the histamine H1 receptor. It was recently approved in 28 countries of the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria in adults and children older than 12 years. Data from preclinical studies confirmed its selectivity for the histamine H1 receptor over other receptors ...
B, Sádaba Díaz de Rada   +2 more
openaire   +2 more sources

Bilastine

Drugs, 2012
Bilastine is an orally administered, second-generation antihistamine used in the symptomatic treatment of seasonal or perennial allergic rhinoconjunctivitis and urticaria. In two well designed phase III trials, 14 days' treatment with bilastine was associated with a significantly lower area under the effect curve (AUEC) for the reflective total symptom
openaire   +2 more sources

Bilastine as a Potential Treatment in Allergic Rhinitis

American Journal of Rhinology & Allergy, 2014
Background Allergic rhinitis is a very frequent disease. H 1 antihistamines have been used for treatment of allergic rhinitis for more than 5 decades.
Krzysztof Kowal, Dubuske, Lawrence
openaire   +2 more sources

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