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Bilastine in allergic rhinoconjunctivitis and urticaria
To cite this article: Bachert C, Kuna P, Zuberbier T. Bilastine in allergic rhinoconjunctivitis and urticaria. Allergy 2010; 65 (Suppl. 93): 1–13.AbstractAllergic rhinoconjunctivitis and urticaria are increasing in prevalence in many developed countries.
Torsten Zuberbier +2 more
exaly +3 more sources
Bilastine: an environmental risk assessment
Bilastine is a new oral selective, non-sedating histamine H1 antagonist for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria. The European Medicines Agency requires an Environmental Risk Assessment (ERA) for all novel medicines for human use.To calculate the bilastine predicted environmental concentration in surface water (PECsw;
María Luisa, Lucero +2 more
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An overview of bilastine metabolism during preclinical investigations
Drug and Chemical Toxicology, 2012Knowledge of the biotransformation of oral H₁ antihistamines is clinically important because it can define their pharmacokinetic profile through possible effects on absorption (i.e., first-pass metabolism) and elimination. Further, clinically significant interactions with inhibitors of cytochrome P450 (CYP) have previously been reported for drugs of ...
Mónica Betanzos
exaly +3 more sources
Bilastine is a novel, nonsedating H-1-antihistamine developed for symptomatic treatment of Allergic Rhinitis and Chronic Idiopathic Urticaria. The objective of this study was to compare the efficacy and safety of bilastine 20 mg vs placebo and ...
Paul van de Heyning +2 more
exaly +2 more sources
Bilastine for the treatment of urticaria
Expert Opinion on Pharmacotherapy, 2013Urticaria is a highly prevalent disease among people. First-choice treatment continues to be centred on the second-generation H1 antihistamines, including a wide group of drugs with a better therapeutic index (or risk:benefit ratio) than the classic ones, even in the high, off-label dosage occasionally required in chronic urticaria.
Ignacio, Jáuregui +8 more
openaire +4 more sources
PURPOSE: Bilastine is a second-generation antihistamine that has been shown to be effective for treatment of allergic conjunctivitis. The objective of this study was to evaluate the pharmacokinetics (PKs) and biodistribution of 0.6% bilastine ...
Gonzalo, Ana +4 more
exaly +2 more sources
Bilastine for the relief of allergy symptoms
Drugs of Today, 2011Bilastine is a potent inhibitor of the histamine H1 receptor. It was recently approved in 28 countries of the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria in adults and children older than 12 years. Data from preclinical studies confirmed its selectivity for the histamine H1 receptor over other receptors ...
B, Sádaba Díaz de Rada +2 more
openaire +2 more sources
Drugs, 2012
Bilastine is an orally administered, second-generation antihistamine used in the symptomatic treatment of seasonal or perennial allergic rhinoconjunctivitis and urticaria. In two well designed phase III trials, 14 days' treatment with bilastine was associated with a significantly lower area under the effect curve (AUEC) for the reflective total symptom
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Bilastine is an orally administered, second-generation antihistamine used in the symptomatic treatment of seasonal or perennial allergic rhinoconjunctivitis and urticaria. In two well designed phase III trials, 14 days' treatment with bilastine was associated with a significantly lower area under the effect curve (AUEC) for the reflective total symptom
openaire +2 more sources
Bilastine as a Potential Treatment in Allergic Rhinitis
American Journal of Rhinology & Allergy, 2014Background Allergic rhinitis is a very frequent disease. H 1 antihistamines have been used for treatment of allergic rhinitis for more than 5 decades.
Krzysztof Kowal, Dubuske, Lawrence
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