Results 1 to 10 of about 4,442 (159)

Evidence Gaps in Clinical Trials of Pharmacologic Treatment for H1-Antihistamine-Refractory Chronic Spontaneous Urticaria: A Systematic Review and Future Perspectives [PDF]

Pharmaceuticals, 2022
No data addressing issues concerning disparities in participant and trial characteristics and trial outcome reporting have been established in clinical trials for H1-antihistamine-refractory chronic spontaneous urticaria (CSU).
Surapon Nochaiwong, Mati Chuamanochan, Chidchanok Ruengorn, Kednapa Thavorn   +3 more
doaj   +2 more sources

Efficacy of different oral H1 antihistamine treatments on allergic rhinitis: a systematic review and network meta-analysis of randomized controlled trials [PDF]

Brazilian Journal of Otorhinolaryngology, 2023
Introduction: Oral H1 antihistamines are the first-line treatment for patients with allergic rhinitis, while it is uncertain which kind and dosage of the antihistamines are more effective in improving symptoms of patients.
Dongdong Hong, Juanling Weng, Meiting Ye, Yuanxian Liu   +3 more
doaj   +2 more sources

Neutrophil/Lymphocyte Ratio as a Biomarker of Response to H1-Antihistamine Therapy in Patients with Chronic Spontaneous Urticaria

Indian Journal of Dermatology
Backgrounds A large proportion of patients with chronic spontaneous urticaria (CSU) are resistant to a standard dose of antihistamine. Acknowledged biomarkers for identifying these patients have not been determined.
Xiaonan Qiu, Qiao Ran, Juanjuan Pan, Guozhen Tan   +3 more
doaj   +2 more sources

Influence of the H1 Antihistamine Mepyramine on the Antibacterial Effect of Florfenicol in Pigs [PDF]

Veterinary Sciences, 2021
The effect of florfenicol against Escherichia coli (E. coli) was investigated in vivo to confirm results of an in vitro study of Bruer et al. (2019), which has shown positive effects of various antibacterial agents in combination with the antihistamine ...
Gustav G. Bruer, Daria Gödecke, Manfred Kietzmann, Jessica Meißner   +3 more
doaj   +2 more sources

Association between Antihistamine Use and Clinical Outcomes in Patients on Maintenance Hemodialysis [PDF]

Kidney Diseases
Introduction: H1 antihistamines are frequently used to treat pruritus in patients on dialysis, but their safety remains unclear. This study aimed to evaluate the effects of H1 antihistamine use on outcomes in patients undergoing maintenance ...
Junseok Jeon, Yu Jeong Lim, Bo Yeon Kim, Ji Young Choi, Jun Young Do, Jung Eun Lee, Seok Hui Kang   +6 more
doaj   +2 more sources

No Time for Lullabies: Tracing down Pharmacological Effects & Uses of H1-Antihistamines in Children Younger than 6 Years

Global Pediatric Health, 2021
Objectives . To provide a qualitative and a quantitative analysis of H1-antihistamines pharmacological uses pattern among children (
Alaa Yehya PhD, Mohammad Numan BSc, Laila Matalqah PhD   +2 more
doaj   +1 more source

Two Cases of Well Controlled Chronic Spontaneous Urticaria Triggered by the Moderna COVID-19 Vaccine

Allergy & Rhinology, 2021
Chronic spontaneous urticaria (CSU, chronic idiopathic urticaria) is a clinical diagnosis characterized by recurrent urticaria of unknown origin, with or without angioedema, that occurs for six weeks or longer.
Cylie Alflen OMS-III, Katheryn Birch DO, Ryan Shilian DO, Shan Shan Wu DO, Robert Hostoffer DO   +4 more
doaj   +1 more source

Association between First-Generation Antihistamine Use in Children and Cardiac Arrhythmia and Ischemic Heart Disease: A Case-Crossover Study

Pharmaceuticals, 2023
Cardiotoxicity from first-generation H1-antihistamines has been debated since the 1990s. However, large-scale studies on this topic in a general pediatric population are lacking.
Ju Hee Kim, Hye Ryeong Cha, Eun Kyo Ha, Ji Hee Kwak, Hakjun Kim, Jeewon Shin, Hye Mi Jee, Man Yong Han   +7 more
doaj   +1 more source

Usage patterns of oral H1-antihistamines in 10 European countries: A study using MASK-air® and Google Trends real-world data

World Allergy Organization Journal, 2022
Real-world data represent an increasingly important source of knowledge in health care. However, assessing their representativeness can be challenging.
Rafael José Vieira, MD, Bernardo Sousa-Pinto, MD PhD, Josep M. Anto, MD PhD, Aziz Sheikh, MD PhD, Ludger Klimek, MD PhD, Torsten Zuberbier, MD PhD, João Almeida Fonseca, MD PhD, Jean Bousquet, MD PhD   +7 more
doaj   +1 more source

Efficacy of switching to bilastine, a histamine H1 receptor antagonist, in patients with chronic spontaneous urticaria (H1-SWITCH): study protocol for a randomized controlled trial

Trials, 2020
Background Chronic spontaneous urticaria (CSU) is characterized by the spontaneous appearance of wheals, angioedema, or both for > 6 weeks. Continuous treatment with H1-antihistamines is used as a first-line treatment for CSU.
Atsushi Fukunaga, Yoshiko Oda, Ken Washio, Takashi Omori, Yasumasa Kakei, Michihiro Hide, Chikako Nishigori   +6 more
doaj   +1 more source