Results 11 to 20 of about 108,387 (211)

H1-antihistamines are associated with lower prevalence of radiographic knee osteoarthritis: a cross-sectional analysis of the Osteoarthritis Initiative data

Arthritis Research & Therapy, 2018
Background There is growing evidence that mast cells (MCs) play a role in knee osteoarthritis (OA). H1-antihistamines block H1-receptors of histamine, which is an important mediator of MCs.
Ivan Shirinsky, Valery Shirinsky
doaj   +2 more sources

The relation between antihistamine medication during early pregnancy & birth defects

Egyptian Journal of Medical Human Genetics, 2015
Antihistamines are a group of medications which can inhibit various histaminic actions at one of two histamine receptors (H1 or H2). H1 receptor antagonists are used for the relief of allergic dermatological and nondermatological conditions.
Rabah M. Shawky, Neveen S. Seifeldin
doaj   +2 more sources

Histamine H1 antagonists and clinical characteristics of febrile seizures

International Journal of General Medicine, 2012
Mohammed A ZolalyDepartment of Pediatrics, College of Medicine, Taibah University, Al-Madinah Al-Munawarah, Kingdom of Saudi ArabiaBackground: The purpose of this study was to determine whether seizure susceptibility due to antihistamines is provoked in ...
Zolaly MA
doaj   +1 more source

Concomitant Usage of H1‐Antihistamines and Immune Checkpoint Inhibitors on Cancer Patient Survival

Cancer Medicine
Purpose Recent research (Li et al. 2021) suggests an upregulated expression and activation of H1 receptors on macrophages in the tumor microenvironment, and concomitant H1‐antihistamine use is associated with improved overall survival in patients with ...
Yin Leung, Terry Cheuk‐Fung Yip, Grace Lai‐Hung Wong, Vincent Wai‐Sun Wong, Vicki Wing‐Ki Hui, Tony Shu‐Kam Mok, Henry Lik‐Yuen Chan, Stephen Lam Chan, Rashid Nok‐Shun Lui   +8 more
doaj   +2 more sources

Pegvaliase-induced immediate hypersensitivity reaction after the discontinuation of antihistamine therapy in a patient with phenylketonuria – Case report

Molecular Genetics and Metabolism Reports
Phenylketonuria (PKU) is an autosomal recessive inborn error of phenylalanine (Phe) metabolism, resulting from the deficient activity of phenylalanine hydroxylase that converts Phe to tyrosine in the liver, leading to elevated levels of Phe.
Nadan Gregoric, Anita Tara, Rebeka Kastelic, Jaka Sikonja, Katarina Peklaj, Mojca Mesojedec, Peter Kopac, Andrej Janez   +7 more
doaj   +2 more sources

Critical appraisal of bepotastine in the treatment of ocular itching associated with allergic conjunctivitis [PDF]

Clinical Ophthalmology, 2011
Jeremy B Wingard, Francis S MahUPMC Eye Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USAAbstract: Bepotastine besilate 1.5% solution is an H1-antihistamine recently approved by the Food and Drug ...
Jeremy B Wingard, Francis S Mah
doaj   +2 more sources

The Efficacy of a Two-Fold Increase of H1-Antihistamine in the Treatment of Chronic Urticaria - the Vietnamese Experience. [PDF]

Open Access Maced J Med Sci, 2019
BACKGROUND: Chronic urticaria, a mast cell-driven condition, is common, debilitating and hard to treat. H1-antihistamines are the first line treatment of chronic urticaria, but often patients do not get satisfactory relief with the recommended dose ...
Thi HT, Thi LP, Van TN, Minh PPT, Trong HN, Van TC, Huu SN, Minh TT, Huu ND, Van TH, Cam VT, Huyen ML, Hau KT, Thanh TN, Thi PH, Thuy LN, Gandolfi M, Satolli F, Feliciani C, Tirant M, Vojvodic A, Lotti T.   +21 more
europepmc   +2 more sources

Evidence Gaps in Clinical Trials of Pharmacologic Treatments for H1-Antihistamine-Refractory CSU

, 2022
 Details of the dataset of  participant and trial characteristics and reporting of outcome in clinical trials of pharmacologic treatments for H1-antihistamine-refractory chronic spontaneous ...
Surapon Nochaiwong (9736187)
core   +1 more source

Supplementary Material for: Skin Treatment with Detergent Induces Dermatitis with H1-Antihistamine-Refractory Itch and Upregulates IL-4 and Th17/Th22 Cytokine Gene Expression in C57BL/6 Mice

, 2022
Introduction: Repeated skin contact to detergents causes chronic irritant contact dermatitis (ICD) associated with itch sensation and eczema. However, the mechanisms of detergent-induced ICD are poorly understood.
Takai T. (13203828), Kamijo S. (13203831), Masutani Y. (13203825), Tominaga M. (13203846), Takada K. (13203843), Takamori K. (13203852), Ikeda S. (4146034), Kimitsu T. (13203834), Ichikawa S. (13203837), Suto H. (13203849), Yoshimura T. (4016309), Shimizu S. (3616652), Ogawa T. (13203840), Ogawa H. (4146028), Okumura K. (4146046)   +14 more
core   +1 more source

Identifying and evaluating key excipients in commercial oral H1 antihistamine syrup formulations: A descriptive study of formulation approaches and selected safety concerns [PDF]

Pharmacia
Excipients are inactive substances required for the preparation of pharmaceutical forms. The efficacy, safety, and quality of syrup formulations depend on their composition, including excipients. Oral H1 antihistamine syrup formulations are most commonly
Rana Hani Mohammed Ali Al-Shaikh Hamed
doaj   +3 more sources