Results 31 to 40 of about 108,387 (211)
DERMACLEAR: AI‐Powered Insights Into Four Chronic Inflammatory Skin Diseases in Spain
JEADV Clinical Practice, EarlyView.Using an AI‐enhanced analysis of electronic health records from nearly 50,000 patients, the DERMACLEAR study provides real‐world insights into the prevalence, clinical complexity, comorbidities and treatment patterns of HS, CU, PsO and AD in Spain.
Ana Giménez‐Arnau +11 more
wiley +1 more source
Pharmacokinetic-Pharmacodynamic Relationships of H1-Antihistamines
Clinical Pharmacokinetics, 1995 Histamine H1-receptor antagonists are reversible, competitive inhibitors of the actions of histamine, a critical mediator in the pathophysiology of the allergic response. This review is mainly devoted to second generation antihistamines that possess a low sedation potential compared with first generation compounds.
Desager, Jean-Pierre, Horsmans, Yves
openaire +2 more sources
Pharmaceutical Biology, 2023 Context Tripterygium glycosides (TG), a traditional Chinese medicine, has been used to treat chronic urticaria (CU) in China, and the evidence of TG for CU needs to be updated thoroughly.Objective To systematically evaluate the efficacy and safety of TG ...
Ming Li, Yan Li, Lujing Xiang
doaj +1 more source
Medicine Advances, EarlyView.This narrative review examines the neurological adverse effects associated with commonly used H1‐antihistamines, focusing on how blood–brain barrier (BBB) penetration and patient age influence central nervous system (CNS) toxicity. The major finding is that first‐generation antihistamines, because of higher CNS penetration, are associated with ...
Syeda Samia Fatima +6 more
wiley +1 more source
Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease
Case Reports in Cardiology, 2016 A 69-year-old man, with severe refractory Crohn’s disease, presented with acute coronary syndrome that required angioplasty. He developed severe tirofiban-induced thrombocytopenia (TIT) heralded by type I allergic reaction that required steroids and a ...
Toni Ibrahim +3 more
doaj +1 more source
Педиатрическая фармакология, 2014 The review is dedicated to treatment of allergic diseases in children, particularly to the use of the 2nd generation antihistamine. It demonstrates that mediator histamine has the crucial role in pathophysiology of the allergic reaction.
Yu. G. Levina +5 more
doaj +1 more source
H1-antihistamines as antischistosomal drugs: in vitro and in vivo studies
Parasites & Vectors, 2020 Background Schistosomiasis is a socioeconomically devastating parasitic infection afflicting hundreds of millions of people and animals worldwide. It is the most important helminth infection, and its treatment relies solely on the drug praziquantel. Oral
Rogério P. Xavier +10 more
doaj +1 more source
, 2017 Background Most data on chronic spontaneous urticaria (CSU) originate from highly selected patient populations treated at specialized centres. Little is known about CSU patient characteristics and the burden of CSU in routine clinical practice.
Bauer, A. +40 more
core +1 more source
Journal of Polymer Science, EarlyView.We present a microfluidic immunoadsorption platform functionalized with a layer‐by‐layer (LbL) nanofilm composed of poly(diallyldimethylammonium chloride) (PDDA) and protein extract (PE) for selective capture of peanut‐specific antibodies directly from the whole blood obtained from a peanut allergy mouse model.
Hesaneh Ahmadi +4 more
wiley +1 more source
Clinical and Translational Allergy, 2012 The electronic records of 398 patients with chronic spontaneous urticaria (CSU) who had had a serum basophil histamine release assay (BHRA) performed as a marker of functional autoantibodies were audited.
Iqbal Kamran +4 more
doaj +1 more source