Results 51 to 60 of about 4,465 (182)

Algorithms in Allergy: Hereditary Angioedema

Allergy, EarlyView.
Konrad Bork, Markus Magerl, Emel Aygören‐Pürsün, Henriette Farkas   +3 more
wiley   +1 more source

Processionary Moth Exposure in Europe: Toxic–Irritant and Immunoglobulin E‐Mediated Endotypes, Diagnosis and Management

Clinical &Experimental Allergy, EarlyView.
Most reactions are toxic–irritant, driven by epithelial injury and neuro‐inflammatory activation. IgE‐mediated allergy is less common but may cause immediate systemic reactions. Endotype differentiation guides diagnosis, risk stratification and management.
Prasad Dasari, Josefine Haas, Wolfgang Rohe, Kai Gloyna, Christoph Viebahn, Susann Forkel, Michael Szardenings, Christine Stadelmann, Michael P. Schön, Timo Buhl   +9 more
wiley   +1 more source

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

International Journal of Dermatology, EarlyView.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller, Helmut Beltraminelli, Wolf‐Henning Boehncke, Maximilian Böhm, Antonio Cozzio, Peter Häusermann, Ahmad Jalili, Antonios G. A. Kolios, Claudia Lang, Eva Loos, Christoph Schlapbach, Curdin Conrad   +11 more
wiley   +1 more source

Influence of initial treatment modality on long-term control of chronic idiopathic urticaria.

PLoS ONE, 2013
BackgroundChronic idiopathic urticaria (CIU) is a common cutaneous disorder but the influence of initial treatment modality on long-term control is not known. The aim of this study was to evaluate clinical features, and the influence of initial treatment
Sujeong Kim, Seunghee Baek, Bomi Shin, Sun-young Yoon, So Young Park, Taehoon Lee, Yoon Su Lee, Yun-Jeong Bae, Hyouk Soo Kwon, You Sook Cho, Hee-Bom Moon, Tae-Bum Kim   +11 more
doaj   +1 more source

Chronic urticaria treatment patterns and changes in quality of life: AWARE study 2-year results

World Allergy Organization Journal, 2020
Background: A Worldwide Antihistamine-Refractory Chronic Urticaria (CU) patient Evaluation (AWARE) is a non-interventional, multicenter study including patients from Europe, Central and Latin America, Asia-Pacific, and the Middle East.
Marcus Maurer, Ana Giménez-Arnau, Luis Felipe Ensina, Chia-Yu Chu, Xavier Jaumont, Paolo Tassinari   +5 more
doaj   +1 more source

Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran, Matjaž Fležar, Manuel Pedro Pereira   +2 more
wiley   +1 more source

Unraveling the Structure of Meclizine Dihydrochloride with MicroED

Advanced Science
Meclizine (Antivert, Bonine) is a first‐generation H1 antihistamine used in the treatment of motion sickness and vertigo. Despite its wide medical use for over 70 years, its crystal structure and the details of protein‐drug interactions remained unknown.
Jieye Lin, Johan Unge, Tamir Gonen
doaj   +1 more source

Pegvaliase-induced immediate hypersensitivity reaction after the discontinuation of antihistamine therapy in a patient with phenylketonuria – Case report

Molecular Genetics and Metabolism Reports
Phenylketonuria (PKU) is an autosomal recessive inborn error of phenylalanine (Phe) metabolism, resulting from the deficient activity of phenylalanine hydroxylase that converts Phe to tyrosine in the liver, leading to elevated levels of Phe.
Nadan Gregoric, Anita Tara, Rebeka Kastelic, Jaka Sikonja, Katarina Peklaj, Mojca Mesojedec, Peter Kopac, Andrej Janez   +7 more
doaj   +1 more source

A Differentiated Approach to the Prescription of Antihistamines in Allergic Diseases in Childhood

Zdorovʹe Rebenka, 2016
The comparative analysis of current data on pharmacodynamics, pharmacokinetics, clinical efficacy and side effects of the first generation drug antihistamine demetinden and the third-generation levocetirizinum is presented.
O.Ye. Abaturov, T.P. Borysova
doaj   +1 more source

Dupilumab in Cholinergic Urticaria: An Exploratory Phase 2 Investigator‐Initiated Study

Allergy, EarlyView.
Annika Gutsche, Weronika Grabowska, Sabine Altrichter, Eva Grekowitz, Stephanie Roll, Guido Heine, Petra Staubach, Wolfgang Pfützner, Randolf Brehler, Andrea Bauer, Nicola Wagner, Gerda Wurpts, Pascale Salameh, Ali Salehzadeh‐Yazdi, Samad S. Jahandideh, Martin Metz   +15 more
wiley   +1 more source