Results 11 to 20 of about 694 (158)
Elucidation of Inverse Agonist Activity of Bilastine [PDF]
Pharmaceutics, 2020 H1-antihistamines antagonize histamine and prevent it from binding to the histamine H1 receptor (H1R). Some of them also act as inverse agonists, which are more potent than pure antagonists because they suppress the constitutive H1R activity.
Hiroyuki Mizuguchi +9 more
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The Journal of Association of Chest Physicians, 2023 In India, the burden of allergic rhinitis (AR) is enormous, comprising 55% of all patients with allergies. Intranasal corticosteroids are the recommended first-line therapy for patients with moderate-to-severe AR, particularly when nasal congestion is ...
Subir Jain +4 more
doaj +2 more sources
Drugs in Context, 2022 Urticaria is a disabling condition, resulting in an impaired quality of life and sleep disruption, and can have an adverse impact on work-related or school-related performance and attendance.
Wai Kwong Cheong +9 more
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Bilastine for the treatment of allergic rhinoconjunctivitis and urticaria: results from an international Delphi study [PDF]
Drugs in ContextBackground: Second-generation oral H1-antihistamines, including bilastine, represent the emerging treatments of allergic rhinitis (including rhinoconjunctivitis) and chronic urticaria in both adults and children.
Giorgio Walter Canonica +7 more
doaj +2 more sources
Bioequivalence and Safety of Bilastine 20 mg Orodispersible Tablets and Conventional Tablets: A Randomized, Single-Dose, Two-Period Crossover Study in Healthy Volunteers Under Fasting Conditions [PDF]
Drugs in R&DBackground and Objective Orodispersible tablets (ODT) rapidly dissolve in the oral cavity and can improve patient’s convenience. This pharmacokinetic study assessed the bioequivalence of a novel 20 mg ODT formulation of bilastine compared with bilastine ...
Manuel Román +6 more
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The new preservative-free ophthalmic formulation of bilastine 0.6% preserves the ocular surface epithelial integrity in a comparative in vitro study [PDF]
Scientific ReportsAllergic conjunctivitis (AC) is the most common form of allergic eye disease and an increasingly prevalent condition. Topical eye drop treatments are the usual approach for managing AC, although their impact on the ocular surface is not frequently ...
Eider Arana +7 more
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Entrapped Transient Chloroform Solvates of Bilastine [PDF]
Crystals, 2021 The knowledge about the solid forms landscape of Bilastine (BL) has been extended. The crystal structures of two anhydrous forms have been determined, and the relative thermodynamic stability among the three known anhydrous polymorphs has been ...
Cristina Puigjaner +4 more
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Photodegradation kinetics of Bilastine in tablets
Drug Analytical ResearchPhotodegradation is the process by which a chemical substance is broken down through exposure to light, typically ultraviolet (UV) radiation. This process is significant in environmental chemistry, where sunlight can degrade pollutants and materials ...
Ariele Nunes Machado +6 more
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Drug Analytical Research, 2017 Bilastine is a novel nonsedative H1-receptor antagonist, which may be used for the symptomatic treatment of chronic idiopathic urticaria (CU). This study describes the validation of an UV spectrophotometric method for quantitative determination of ...
Andressa Tassinari da Silva +5 more
doaj +9 more sources
Drugs in Context, 2021 Background: Bilastine, a non-sedating H1-antihistamine, is indicated to treat the symptoms of allergic disorders (e.g. rhinoconjunctivitis and urticaria) in adults and adolescents and, more recently, in children.
Amalia Leceta +3 more
doaj +1 more source