Results 271 to 280 of about 1,013,035 (362)

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson   +1 more
wiley   +1 more source

Hepatic Aquaporin 8 Promotes Alcohol Consumption and Ameliorates Alcohol-Induced Liver Injury by Facilitating Acetaldehyde Excretion. [PDF]

open access: yesInt J Biol Sci
Chen C   +13 more
europepmc   +1 more source

The Insistence of Blackness and the Persistence of Antiblackness in Ireland

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT This paper positions Ireland as a critical site for examining the insistence of blackness and an antiblackness created and sustained through Irish ethnonationalist imaginaries and exclusionary processes. Drawing on connected sociologies and Irish Black Studies, this enquiry argues that antiblackness in Ireland operates as a generational force,
Philomena Mullen
wiley   +1 more source

Efficacy, Safety and Tolerability of Volixibat, an IBAT Inhibitor, in Patients With Intrahepatic Cholestasis of Pregnancy. [PDF]

open access: yesLiver Int
Ovadia C   +11 more
europepmc   +1 more source

Characterization of inflammatory pseudotumors in a large animal model of liver cancer

open access: yesAnimal Models and Experimental Medicine, EarlyView.
CT images in arterial and portal venous phases of liver lesions in Oncopig. Abstract Background The development of relevant and robust large animal models of hepatocellular carcinoma is needed to test new therapeutic strategies for this disease. Transgenic approaches hold promise in addressing this complex problem. One such model, the Oncopig, has been
Erik N. K. Cressman   +4 more
wiley   +1 more source

Factors associated with the need for electrohydraulic lithotripsy in endoscopic papillary large balloon dilation for giant common bile duct stones. [PDF]

open access: yesTherap Adv Gastroenterol
Ishihara T   +18 more
europepmc   +1 more source

Two‐stage portal flow modulation for volume‐augmented grafts in living donor liver transplantation: Rat model validation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study presents a two‐stage portal flow modulation strategy for graft procurement in living donor liver transplantation with the aim of expanding left lateral lobe grafts, thereby circumventing technical and anatomical limitations of conventional approaches.
Yuqi Gong   +6 more
wiley   +1 more source

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen   +12 more
wiley   +1 more source

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