Results 61 to 70 of about 1,307,425 (404)

HISTOPATHOLOGY POST INTRAPERITONEAL INFECTION WITH Providencia rettgeri IN MICE [PDF]

Basrah Journal of Veterinary Research, 2016
The Providencia rettgeri (P.rettgeri) is an opportunistic pathogen of human and animals and has a clinical importance as a nosocomial pathogen causing infections in the urinary system after catheterization and in immunocompromised patients less than ...
Zainab Ismail Ibrahim
doaj   +1 more source

Bile acids and their receptors: modulators and therapeutic targets in liver inflammation

Seminars in Immunopathology, 2022
Bile acids participate in the intestinal emulsion, digestion, and absorption of lipids and fat-soluble vitamins. When present in high concentrations, as in cholestatic liver diseases, bile acids can damage cells and cause inflammation.
A. Bertolini, R. Fiorotto, M. Strazzabosco   +2 more
semanticscholar   +1 more source

A novel GPER antagonist protects against the formation of estrogen-induced cholesterol gallstones in female mice

Journal of Lipid Research, 2020
Many clinical studies and epidemiological investigations have clearly demonstrated that women are twice as likely to develop cholesterol gallstones as men, and oral contraceptives and other estrogen therapies dramatically increase that risk.
Chelsea DeLeon, Helen H. Wang, Joseph Gunn, McKenna Wilhelm, Aidan Cole, Stacy Arnett, David Q-H. Wang, Christopher K. Arnatt   +7 more
doaj   +1 more source

Mathematical Modeling of Deposits Accumulation on the Plastic Biliary Stent Surface for Predicting Its Occlusion [PDF]

Известия Саратовского университета. Новая серия: Математика. Механика. Информатика, 2020
Endoprosthetics with plastic stents has been used to restore bile drainage through the percutaneous or endoscopic method since the late 1970s. The long-term results cannot be considered satisfactory due to the high incidence of jaundice recurrence which ...
Kuchumov, Aleksei Gennadevich
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Ezetimibe in Combination With Simvastatin Reduces Remnant Cholesterol Without Affecting Biliary Lipid Concentrations in Gallstone Patients

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background In randomized trials (SHARP [Study of Heart and Renal Protection], IMPROVE‐IT [Improved Reduction of Outcomes: Vytorin Efficacy International Trial]), combination of statin and ezetimibe resulted in additional reduction of cardiovascular ...
Osman Ahmed, Karin Littmann, Ulf Gustafsson, Camilla Pramfalk, Katariina Öörni, Lilian Larsson, Mirko E. Minniti, Staffan Sahlin, German Camejo, Paolo Parini, Mats Eriksson   +10 more
doaj   +1 more source

Stimulation of ABCB4/MDR3 ATPase activity requires an intact phosphatidylcholine lipid

Journal of Lipid Research, 2020
ABCB4/MDR3 is located in the canalicular membrane of hepatocytes and translocates PC-lipids from the cytoplasmic to the extracellular leaflet.
Martin Prescher, Sander H.J. Smits, Lutz Schmitt   +2 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Nexus between renewable energy and agricultural productivity in Somalia: Evidence from Fragile Foundations

Cogent Food & Agriculture
Somalia has considerable land deterioration due to soil erosion and deforestation. These environmental stresses reduce agricultural productivity. Despite these challenges, the nation has renewable energy sources that haven’t been used yet.
Bile Abdisalan Nor
doaj   +1 more source

Effect of phospholipids and bile acids on cholesterol nucleation time and vesicular/micellar cholesterol in gallbladder bile of patients with cholesterol stones [PDF]

, 1993
Supersaturation and rapid nucleation of cholesterol in bile are of key importance in the pathogenesis of cholesterol gallstones. While the effects of bile acids and phospholipids on cholesterol saturation of bile have been extensively studied, their ...
Huber, P., Jüngst, Dieter, Lang, Thomas, Lange, V., Paumgartner, Gustav   +4 more
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