Results 61 to 70 of about 1,013,035 (362)

Novel Bile Acids from Bear Bile Powder and Bile of Geese

Chemical and Pharmaceutical Bulletin, 2009
Two new bile acids, tauroselocholic acid (1) and tauroansocholic acid (2), a new natural bile acid, cygnocholic acid (3) were respectively isolated from bear bile powder Selenaretos thibetanus CUVIER and bile of geese Anser anser domesticus, together with seven known compounds.
Dan, Bi, Xing-Yun, Chai, Yue-Lin, Song, Yu, Lei, Peng-Fei, Tu   +4 more
openaire   +3 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]

, 1994
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Del Pozo, Reginals, Jüngst, Dieter, Lange, Volker, Miquel, Juan Francisco, Paumgartner, Gustav, Ritter, Christoph von   +5 more
core   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Gallbladder diseases detected by ultrasound and correlated risk factors [PDF]

Romanian Journal of Medical Practice
Background. Gallbladder diseases are relatively common, most of which are asymptomatic, others may be presented with right hypochondriac pain. Obesity, metabolic syndrome, long-term fasting, rapid weight reduction, bariatric surgery and drugs are ...
Sahar Ahmed MAHDI, Israa JAAFAR
doaj   +1 more source

Profiles of biliary microbiota in biliary obstruction patients with Clonorchis sinensis infection

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundClonorchis sinensis (C. sinensis) is a epidemiologically significant food-borne parasite, causing several hepatobiliary diseases. Biliary microbiota community structure might be influenced by infection with pathogens.
Rui Chen, Xiang Li, Xiang Li, Jian Ding, Jie Wan, Jie Wan, Xueli Zhang, Xu Jiang, Shanshan Duan, Xinyi Hu, Yannan Gao, Beibei Sun, Xi Lu, Ruifeng Wang, Yang Cheng, Xiaoli Zhang, Su Han, Su Han, Su Han   +18 more
doaj   +1 more source

Purine nucleoside phosphorylase: A new marker for free oxygen radical injury to the endothelial cell [PDF]

, 1990
The effect of ischemia and reperfusion on purine nucleoside phosphorylase was studied in an isolated perfused rat liver model. This enzyme is localized primarily in the cytoplasm of the endothelial and Kupffer cells; some activity is associated with the ...
Abouna, Adkison, Eiseman, Granger, Green, Hanks, Hoffee, James T. Snyder, Kamada, Kamiike, Kamiike, Kizaki, Lanir, Lee, Lee, LeMasters, LeMasters, Leonard Makowka, Marotto, Marubayashi, Marubayashi, McCord, Nishida, Parks, Prakash N. Rao, Randy S. Rubin, Rubio, Teperman, Thomas E. Starzl, Thomas R. Walsh, Thomas Weber, Turner, Van Thiel   +32 more
core   +1 more source

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination[S]

Journal of Lipid Research, 2015
Previous studies suggest an interdependent relationship between liver and intestine for cholesterol elimination from the body. We hypothesized that a combination of ursodiol (Urso) and ezetimibe (EZ) could increase biliary secretion and reduce ...
Yuhuan Wang, Xiaoxi Liu, Sonja S. Pijut, Jianing Li, Jamie Horn, Emily M. Bradford, Markos Leggas, Terrence A. Barrett, Gregory A. Graf   +8 more
doaj   +1 more source

Clinical Conditions Associated With a High Antinuclear Antibody Titer in Individuals Without Autoimmune Disease

Arthritis Care &Research, EarlyView.
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung, John P. Shelley, Gul Karakoc, John Still, Xiaodi Ruan, Jonathan Mosley, C. Michael Stein, Vivian K. Kawai   +7 more
wiley   +1 more source